Patent classifications
C
CHEMISTRY; METALLURGY
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C07
ORGANIC CHEMISTRY
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C07H
SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
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5/00
Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
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C07H5/08
to sulfur, selenium or tellurium
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C07H5/08

Ruthenium carbon monoxide releasing molecules and uses thereof
09611286 · 2017-04-04 · ·

The present invention provides novel ruthenium compounds of Formula (I): ##STR00001##
or salts, isomers, hydrates, or solvates thereof, or combinations thereof; wherein E, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, X.sub.1, and X.sub.2 are as defined herein, and pharmaceutical compositions thereof. Also provided are methods of use and treatment. Such compounds have been found useful in the treatment of malaria infection. Such compounds may also be useful in the treatment of inflammatory conditions, such as acute lung injury and acute resipiratory distress syndrome, which optionally may be associated with a malaria infection.

Ruthenium carbon monoxide releasing molecules and uses thereof
09611286 · 2017-04-04 · ·

The present invention provides novel ruthenium compounds of Formula (I): ##STR00001##
or salts, isomers, hydrates, or solvates thereof, or combinations thereof; wherein E, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, X.sub.1, and X.sub.2 are as defined herein, and pharmaceutical compositions thereof. Also provided are methods of use and treatment. Such compounds have been found useful in the treatment of malaria infection. Such compounds may also be useful in the treatment of inflammatory conditions, such as acute lung injury and acute resipiratory distress syndrome, which optionally may be associated with a malaria infection.