Patent classifications
C08B30/18
METHOD OF PREPARING FERRIC CARBOXYMALTOSE
Provided is a method of preparing ferric carboxymaltose with weight average molecular weight between 100,000 and 400,000. The method includes reacting an oxidized maltodextrin solid with an iron (III) salt solution in acidic and basic conditions in sequence to afford ferric carboxymaltose, wherein the oxidized maltodextrin solid has a dextrose equivalent of less than 4. The ferric carboxymaltose prepared by the method can withstand high-temperature sterilization with high stability and facilitate storage.
STARCH-BASED DOUBLE-LOADED FUNCTIONAL NANO PARTICLE AS WELL AS PREPARATION METHOD AND APPLICATION
The preparation method of a starch-based double-loaded functional nanoparticle includes: performing restrictive hydrolysis treatment on egg high-density lipoprotein using proteases to obtain the polypeptide; performing self-assembling on a mixed system containing the polypeptide and quercetin under the alkaline condition to form a micelle nanoparticle; performing covalent grafting reaction on a mixed system containing the micelle nanoparticle and anthocyanin under the alkaline condition to form a graft; and electrostatically compounding carboxymethyl dextrin with the graft to obtain the starch-based double-loaded functional nanoparticle. In the preparation method, raw materials derived from natural sources are used, and the self-assembled colloid nanoparticle with good properties can be obtained by adjusting the pH without any organic reagents. The obtained product has a nanoparticle size, has high antioxidant activity and stability against environmental stress, and can be widely applied to the fields of delivery of nutrients, stabilization of biologically active substances and the like.
STARCH-BASED DOUBLE-LOADED FUNCTIONAL NANO PARTICLE AS WELL AS PREPARATION METHOD AND APPLICATION
The preparation method of a starch-based double-loaded functional nanoparticle includes: performing restrictive hydrolysis treatment on egg high-density lipoprotein using proteases to obtain the polypeptide; performing self-assembling on a mixed system containing the polypeptide and quercetin under the alkaline condition to form a micelle nanoparticle; performing covalent grafting reaction on a mixed system containing the micelle nanoparticle and anthocyanin under the alkaline condition to form a graft; and electrostatically compounding carboxymethyl dextrin with the graft to obtain the starch-based double-loaded functional nanoparticle. In the preparation method, raw materials derived from natural sources are used, and the self-assembled colloid nanoparticle with good properties can be obtained by adjusting the pH without any organic reagents. The obtained product has a nanoparticle size, has high antioxidant activity and stability against environmental stress, and can be widely applied to the fields of delivery of nutrients, stabilization of biologically active substances and the like.
Aqueous iron carbohydrate complexes, their production and medicaments containing them
A water soluble iron carbohydrate complex obtainable from an aqueous solution of iron (III) salt and an aqueous solution of the oxidation product of one or more maltodextrins using an aqueous hypochlorite solution at a pH-value within the alkaline range, where, when one maltodextrin is applied, its dextrose equivalent lies between 5 and 20, and when a mixture of several maltodextrins is applied, the dextrose equivalent of the mixture lies between 5 and 20 and the dextrose equivalent of each individual maltodextrin contained in the mixture lies between 2 and 40, process for its production and a medicament for the treatment and prophylaxis of iron deficiency conditions.
Aqueous iron carbohydrate complexes, their production and medicaments containing them
A water soluble iron carbohydrate complex obtainable from an aqueous solution of iron (III) salt and an aqueous solution of the oxidation product of one or more maltodextrins using an aqueous hypochlorite solution at a pH-value within the alkaline range, where, when one maltodextrin is applied, its dextrose equivalent lies between 5 and 20, and when a mixture of several maltodextrins is applied, the dextrose equivalent of the mixture lies between 5 and 20 and the dextrose equivalent of each individual maltodextrin contained in the mixture lies between 2 and 40, process for its production and a medicament for the treatment and prophylaxis of iron deficiency conditions.
USE OF MALTODEXTRIN AS AN EXCIPIENT
The present invention relates to the use of maltodextrin as an excipient. In particular, the present invention relates to the use of maltodextrin as an excipient in probiotic formulations.
The present invention also relates to a method to provide a probiotics formulation with improved dispersibility and/or shelf life comprising adding maltodextrin to probiotic formulations.
MALTODEXTRIN SYRUP HAVING A DE LESS THAN 20 WHILE HAVING PROPERTIES LIKE A CORN SYRUP OF DE 30-45
A new type of maltodextrin syrup is described having functional properties of a corn syrup having a DE of between 35-45 while having a DE value less than 20. In the most general embodiment, the syrup contains no more than 70% of total saccharides with a DP of less than 10 while at the same time having least 50% of the saccharides do have a DP of less than 10. The remainder of the saccharides have a DP of 10 or more. For those saccharides having a DP of less than 10 the distribution is weighted toward the higher end with saccharides having a DP of 5 to 9 being more than the saccharides having a DP of 1 to 4.
MALTODEXTRIN SYRUP HAVING A DE LESS THAN 20 WHILE HAVING PROPERTIES LIKE A CORN SYRUP OF DE 30-45
A new type of maltodextrin syrup is described having functional properties of a corn syrup having a DE of between 35-45 while having a DE value less than 20. In the most general embodiment, the syrup contains no more than 70% of total saccharides with a DP of less than 10 while at the same time having least 50% of the saccharides do have a DP of less than 10. The remainder of the saccharides have a DP of 10 or more. For those saccharides having a DP of less than 10 the distribution is weighted toward the higher end with saccharides having a DP of 5 to 9 being more than the saccharides having a DP of 1 to 4.
MODIFIED NATURAL MATERIAL AND USE THEREOF
An oil repellent agent including a modified natural product having at least one hydroxyl group, wherein a hydrogen atom of the hydroxyl group is replaced with an R group represented by —Y—Z, wherein Y represents a direct bond, —C(═O)—, —C(═O)—NR′— or —C(═S)—NR′—, where R′ represents a hydrogen atom or a C.sub.1 to C.sub.4 alkyl group); and Z represents a hydrocarbon group having 1 to 40 carbon atoms and optionally having a substituent or a polysiloxane. The natural material is a natural product other than starch and preferably is a monosaccharide, a polysaccharide, glycerin or polyglycerin. Also disclosed is a textile product to which the oil-resistant agent is attached, an oil-resistant paper and a method of treating paper with the oil-resistant agent.
MODIFIED NATURAL MATERIAL AND USE THEREOF
An oil repellent agent including a modified natural product having at least one hydroxyl group, wherein a hydrogen atom of the hydroxyl group is replaced with an R group represented by —Y—Z, wherein Y represents a direct bond, —C(═O)—, —C(═O)—NR′— or —C(═S)—NR′—, where R′ represents a hydrogen atom or a C.sub.1 to C.sub.4 alkyl group); and Z represents a hydrocarbon group having 1 to 40 carbon atoms and optionally having a substituent or a polysiloxane. The natural material is a natural product other than starch and preferably is a monosaccharide, a polysaccharide, glycerin or polyglycerin. Also disclosed is a textile product to which the oil-resistant agent is attached, an oil-resistant paper and a method of treating paper with the oil-resistant agent.