Aspects of the invention include a method for synthesizing a peptide brush polymer, the method comprising: exposing a mixture comprising peptide-containing monomers, one or more photoinitiators, and one or more chain transfer agents to a light sufficient to induce photopolymerization, and photopolymerizing the peptide-containing monomers in the mixture; wherein: the resulting peptide brush polymer comprises at least one peptide-containing polymer block; the at least one peptide-containing polymer block is characterized by a degree of polymerization of at least 10 and a peptide graft density of 50% to 100%; and at least one peptide moiety of the at least one peptide-containing polymer block has 5 or more amino acid groups.

Disclosed are antimicrobial articles and surfaces, as well as methods of making such articles and surfaces.

The present disclosure relates to an antibacterial polymer composition, more specifically, to an antibacterial polymer composition enabling preparation of a coating layer exhibiting excellent antibacterial property. The antibacterial polymer composition may use a polymer including a specific number of repeat units as an antibacterial agent. Accordingly, unlike coating compositions using antibacterial monomers/antibacterial oligomers, elution of an antibacterial agent from the coating layer may be prevented even after time passes, and thus, it can continuously exhibit antibacterial property, and yet, is difficult to be absorbed in human body.

A polymeric delivery system delivers a biologic to cells. In some embodiments, the polymeric delivery system includes polyplexes. Each polyplex includes at least one charged polymer and at least one biologic. The at least one charged polymer includes a polyester copolymer of a polyol and a polycarboxylic acid modified with at least one charged moiety having an opposite charge from a net charge of the at least one biologic. In other embodiments, the polymeric delivery system includes self-assembled particles including a block copolymer and a biologic associated with the block copolymer. The block copolymer includes a first block of a polyester copolymer of a polyol and a polycarboxylic acid and a second block of a second monomer or a second polymer.

A method of making a sensor includes subjecting a metal substrate to a solution having glycopolymer chains and attaching the glycopolymer chains to the metal substrate to form a glycopolymer-functionalized metal substrate that can bind a lectin target. A lectin target can be a food allergen or a toxin. The metal substrate can include a plasmonic metal. A method of using the sensor includes incubating a portion of the sensor in a sample fluid and another portion of the sensor in a control fluid. Spectral data sets are generated via Raman Spectroscopy for each portion of the sensor. The presence and concentration of a lectin target in the sample fluid is determined by comparing the spectral data sets.

A method of making a sensor includes subjecting a metal substrate to a solution having glycopolymer chains and attaching the glycopolymer chains to the metal substrate to form a glycopolymer-functionalized metal substrate that can bind a lectin target. A lectin target can be a food allergen or a toxin. The metal substrate can include a plasmonic metal. A method of using the sensor includes incubating a portion of the sensor in a sample fluid and another portion of the sensor in a control fluid. Spectral data sets are generated via Raman Spectroscopy for each portion of the sensor. The presence and concentration of a lectin target in the sample fluid is determined by comparing the spectral data sets.

Disclosed are antimicrobial articles and surfaces, as well as methods of making such articles and surfaces.

Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.

Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.

Disclosed herein are zwitterionic monomers, non-zwitterionic monomers, polyzwitterionic polymers formed therefrom; surface functionalization; surface modification; and articles containing any such compositions or surfaces formed therefrom.