Various embodiments disclosed relate to a resin having a structure of at least one of Formula I and Formula II: In Formula I or Formula II R.sup.1, R.sup.3, R.sup.4, R.sup.5, and R.sup.6 can each be independently selected from the group consisting of hydrogen and substituted or unsubstituted (C.sub.1-C.sub.10)alkyl. R.sup.2 is (C.sub.1-C.sub.10) alkylene. L is a substituted or unsubstituted (C.sub.1-C.sub.10)alkylene or (C.sub.3-C.sub.10)cycloalkylene. In Formula I or Formula II, n or m is greater than or equal to 0, and wherein the resin has an average molecular weight of less than 10,000 g/mol. ##STR00001##

The present invention provides an inkjet ink comprising: 10-50% by weight of one or more monomers each having a log P.sub.octanol/water value of 5.0 or more, based on the total weight of the ink; a photoinitiator package comprising one or more photoinitiators each having a log P.sub.octanol/water value of less than 4.0, and one or more photoinitiators selected from (I) and mixtures thereof, wherein n is a value from 1 to 10 and a+b+c is a value from 1 to 20; and wherein the one or more photoinitiators each having a log P.sub.octanol/water value of less than 4.0 are present in the ink in an amount of 0.5-4.5% by weight, based on the total weight of the ink. The present invention also provides a method of printing the inkjet ink of the present invention.

The present invention provides an inkjet ink comprising: 10-50% by weight of one or more monomers each having a log P.sub.octanol/water value of 5.0 or more, based on the total weight of the ink; a photoinitiator package comprising one or more photoinitiators each having a log P.sub.octanol/water value of less than 4.0, and one or more photoinitiators selected from (I) and mixtures thereof, wherein n is a value from 1 to 10 and a+b+c is a value from 1 to 20; and wherein the one or more photoinitiators each having a log P.sub.octanol/water value of less than 4.0 are present in the ink in an amount of 0.5-4.5% by weight, based on the total weight of the ink. The present invention also provides a method of printing the inkjet ink of the present invention.

A method for indirect additive manufacturing of an object, the method comprising: (i) separately feeding a powder from which said object is to be manufactured and either a difunctional curable monomer according to Formula (I) or an adhesive polymer binder into an additive manufacturing device; (ii) dispensing selectively positioned droplets of said difunctional curable monomer or adhesive polymer binder, from a printhead of said additive manufacturing device, into a bed of said powder to bind particles of said powder with said difunctional curable monomer or adhesive polymer binder to produce a curable preform having a shape of the object to be manufactured; and, in the case of the difunctional curable monomer, (iii) curing said curable preform to form a crosslinked object.

A method for refolding an antibody, a process for producing a refolded antibody, a refolded antibody, and uses thereof are provided. A method for refolding an antibody in a liquid phase comprises the steps of denaturing an inactive antibody binding directly or through a linker to a peptide, the peptide having an isoelectric point lower than the isoelectric point of the inactive antibody, and dispersing in a liquid phase the peptide-binding inactive antibody denatured in the step above. Also provided is a process for producing a refolded antibody.

A method for refolding an antibody, a process for producing a refolded antibody, a refolded antibody, and uses thereof are provided. A method for refolding an antibody in a liquid phase comprises the steps of denaturing an inactive antibody binding directly or through a linker to a peptide, the peptide having an isoelectric point lower than the isoelectric point of the inactive antibody, and dispersing in a liquid phase the peptide-binding inactive antibody denatured in the step above. Also provided is a process for producing a refolded antibody.

The invention relates to a multifunctional acrylic product having a number-average functionality f of acrylate groups greater than 2.1, which is the product of reaction by esterification and by etherification, via Michael addition reaction, between a) a polyol or a mixture of polyols R(OH).sub.m having a functionality m of at least 3 for a polyol alone or having an average functionality greater than 2.1 for a mixture of polyols, and b) the acrylic acid (R.sub.1OH) in the presence of c) at least one cyclic polycarboxylic anhydride or of its polyacid form having a carboxy functionality z of at least 2 and up to 4, the ratio r.sub.1 of number of carboxy groups of said anhydride or polyacid c) with respect to those of the acrylic acid b) r.sub.1=CO.sub.2Hc/CO.sub.2Hb being from 0.01 to 0.4 with overall r=CO.sub.2H/OH<1, said acrylic product comprising in its composition both: units A) of oligoether-ester acrylate that are derived from a) and b) and units B) of oligoester acrylate that are derived from c),
said acrylic product being a mixture of acrylic products comprising at least one acrylic product p1 chemically linking, in its molecular structure, the two types of units A) and B) as defined above.

The invention also relates to a process for preparing said product, to crosslinkable compositions comprising same and to the use thereof in coatings, sealing, moulding or composite compositions, chemical sealing compositions, 3D printing compositions or compositions for 3D objects produced layer-by-layer. One particular advantage of these compositions is their low shrinkage despite their high functionality.

The invention relates to water soluble crosslinkable prepolymers for the preparation of chemically stable crosslinked polymer gels, a process for preparing the same, compositions containing the same and their use such as a medical or dental filler composition.

A tool provided that individually creates three-dimensional structural elements which are sequentially positioned into formation of a shaped object.

A tool provided that individually creates three-dimensional structural elements which are sequentially positioned into formation of a shaped object.