The disclosure relates to cationic polymers functionalized with substituted phenylboronic acid groups and to methods of using the same to treat metabolic and gastrointestinal disorders.

The disclosure relates to cationic polymers functionalized with substituted phenylboronic acid groups and to methods of using the same to treat metabolic and gastrointestinal disorders.

A composition includes: a compound including an aromatic ring; and a first polymer including a first structural unit represented by formula (1) and a second structural unit represented by formula (2). A content of the first polymer with respect to 100 parts by mass of the compound is no less than 0.1 parts by mass and no greater than 200 parts by mass. R.sup.1 represents a hydrogen atom or a substituted or unsubstituted monovalent hydrocarbon group; and R.sup.2 represents a substituted or unsubstituted monovalent hydrocarbon group. R.sup.3 represents a hydrogen atom or a substituted or unsubstituted monovalent hydrocarbon group; L represents a single bond or a divalent linking group; Ar represents a group obtained by removing (n+1) hydrogen atoms from a substituted or unsubstituted aromatic ring; R.sup.4 represents a hydroxy group or a monovalent hydroxyalkyl group; and n is an integer of 1 to 8.

##STR00001##

A composition includes: a compound including an aromatic ring; and a first polymer including a first structural unit represented by formula (1) and a second structural unit represented by formula (2). A content of the first polymer with respect to 100 parts by mass of the compound is no less than 0.1 parts by mass and no greater than 200 parts by mass. R.sup.1 represents a hydrogen atom or a substituted or unsubstituted monovalent hydrocarbon group; and R.sup.2 represents a substituted or unsubstituted monovalent hydrocarbon group. R.sup.3 represents a hydrogen atom or a substituted or unsubstituted monovalent hydrocarbon group; L represents a single bond or a divalent linking group; Ar represents a group obtained by removing (n+1) hydrogen atoms from a substituted or unsubstituted aromatic ring; R.sup.4 represents a hydroxy group or a monovalent hydroxyalkyl group; and n is an integer of 1 to 8.

##STR00001##

The present invention concerns a process for the preparation of a copolymer comprising the steps of copolymerizing under suitable reaction conditions at least one first type of olefin monomer and at least one second type of functionalized olefin monomer using a catalyst system to obtain a polyolefin main chain having one or multiple functionalized short chain branches, the catalyst system comprising: i) a single-site catalyst or catalyst precursor comprising a metal selected from Ti3+ or Cr3+; ii) a co-catalyst; iii) optionally a scavenger.

The present invention concerns a process for the preparation of a copolymer comprising the steps of copolymerizing under suitable reaction conditions at least one first type of olefin monomer and at least one second type of functionalized olefin monomer using a catalyst system to obtain a polyolefin main chain having one or multiple functionalized short chain branches, the catalyst system comprising: i) a single-site catalyst or catalyst precursor comprising a metal selected from Ti3+ or Cr3+; ii) a co-catalyst; iii) optionally a scavenger.

An aqueous emulsion is made by emulsion polymerizing at least one free-radically polymerizable monomer and one or more di- or higher-functional chain-extending monomers in the presence of an aqueous solution of an oligomer made from a mixture of free-radically polymerizable monomers including acid-functional free-radically polymerizable comonomers, adhesion-promoting free-radically polymerizable comonomers and other free-radically polymerizable comonomers. The aqueous emulsion is substantially free of adipic dihydrazide, has a minimum film forming temperature≤55° C., and on drying has a Koenig hardness of at least 40 sec.

An aqueous emulsion is made by emulsion polymerizing at least one free-radically polymerizable monomer and one or more di- or higher-functional chain-extending monomers in the presence of an aqueous solution of an oligomer made from a mixture of free-radically polymerizable monomers including acid-functional free-radically polymerizable comonomers, adhesion-promoting free-radically polymerizable comonomers and other free-radically polymerizable comonomers. The aqueous emulsion is substantially free of adipic dihydrazide, has a minimum film forming temperature≤55° C., and on drying has a Koenig hardness of at least 40 sec.

The disclosure relates to cationic polymers functionalized with substituted phenylboronic acid groups and to methods of using the same to treat metabolic and gastrointestinal disorders.

The disclosure relates to cationic polymers functionalized with substituted phenylboronic acid groups and to methods of using the same to treat metabolic and gastrointestinal disorders.