C08J2201/0484

Scrub sponge and preparation method therefor

Disclosed are a scrub sponge and a preparation method therefor. The method for preparing the scrub sponge includes the operations of: obtaining a first mixture by stirring alkalizer, porogen, konjac powder, scrub granule and water, and filling the first mixture into a mold to form a preform, where the preform includes a first sponge layer; forming a parison by sequentially cooking and freezing the preform; and sequentially unfreezing, dehydrating and drying the parison to obtain the scrub sponge.

Method for preparing porous scaffold for tissue engineering, cell culture and cell delivery

The present invention relates to a method for preparing a porous scaffold for tissue engineering. It is another object of the present invention to provide a porous scaffold obtainable by the method as above described, and its use for tissue engineering, cell culture and cell delivery. The method of the invention comprises the steps consisting of: a) preparing an alkaline aqueous solution comprising an amount of at least one polysaccharide, an amount of a cross-linking agent and an amount of a porogen agent b) transforming the solution into a hydrogel by placing said solution at a temperature from about 4° C. to about 80° C. for a sufficient time to allow the cross-linking of said amount of polysaccharide and c) submerging said hydrogel into an aqueous solution d) washing the porous scaffold obtained at step c).

FABRICATION OF AEROGELS AND AEROGEL COMPOSITES BY AMBIENT PRESSURE SUBLIMATION OF FROZEN SOLVENTS
20220356320 · 2022-11-10 ·

Drying polar solvents which do not form hydrogen bonds with a wet gel or aerogel, or eutectics or solvent mixtures with the drying solvents, are utilized in a solvent exchange with wet gels used in the formation of aerogels. Preferably the drying solvents are non-polar solvents. The drying solvent or solvent mixtures results in profoundly less shrinkage, thereby allowing for the production of aerogels of preferred materials properties.

SYSTEM AND METHOD FOR MANUFACTURING WATER-BASED HYDROPHOBIC AEROGELS AND AEROGEL COMPOSITES

Embodiments of the present invention provide users with a system and method for manufacturing water-based hydrophobic aerogels and aerogel composites. The system and method can be carried out in a manner which is more rapid than typical ways and can be readily scalable. The method of manufacture is useful for producing water based hydrophobic aerogels and aerogel composites on a large scale with good homogeneity and consistency. Advantageously, the method of manufacture also has the benefit of a shorter processing time due to the vacuum homogenizing and mixing processes, the use of microwave assisted vacuum freeze drying for ease of synthesis of water-based hydrophobic aerogels.

METHOD FOR PREPARING MICROCARRIER SUITABLE FOR THREE-DIMENSIONAL CELL CULTURE AND REACTION APPARATUS

Provided herein is a method for preparing microcarrier particles, comprising the steps of allowing the dispersed phase liquid flow through a multi-hole plate at a low temperature to form liquid microspheres in a continuous phase, and enabling a synthetic polymer and/or natural biological macromolecules within the liquid microspheres to be subject to a curing reaction at a low temperature to form particles. Further provided herein are the method for preparing an emulsion and an apparatus and process system for preparing microcarrier particles, which can be used for preparing emulsions and microcarrier particles on a large scale.

Method for preparing modified cellulose aerogel for glycoprotein separation

A method for preparing a modified cellulose aerogel for glycoprotein separation is provided. In this method, cellulose aerogel is employed as a substrate. The cellulose aerogel is known to have a three-dimensional network structure with extremely high porosity and specific surface area and extremely low density. So, by using the cellulose aerogel as a substrate, it is possible to provide the glycoproteins to be separated with more binding sites. PEI dendrimer has abundant functional groups and can easily be modified. By modifying the cellulose aerogel substrate with the PEI dendrimer, it is possible to improve the density of the phenylboronic acid bound to the substrate, thereby leading to higher affinity toward the glycoproteins to be separated.

CHITOSAN-POLYACRYLAMIDE COMPOSITE POROUS HYDROGEL, PREPARATION AND USE THEREOF, AND METAL ION-DETECTING REAGENT AND METHOD

The present application relates to the technical field of wastewater treatment and rapid pollutant detection, in particular to a chitosan-polyacrylamide composite porous hydrogel, preparation and use thereof, and a metal ion-adsorbing and detecting reagent and method. The chitosan-polyacrylamide composite porous hydrogel of the present application is prepared by in situ polymerization of a chitosan sol, an acrylamide, a crosslinking agent and a surfactant into a mixed solution comprising liquid droplets, followed by steps of curing, washing, and freeze-drying. The present application further provides a metal ion-detecting reagent, which is obtained by adsorbing a color developing agent into the chitosan-polyacrylamide composite porous hydrogel as described above, wherein the color developing agent is a dye that changes color when encountering metal ions. The chitosan-polyacrylamide composite porous hydrogel of the present application has balanced mechanical properties and porosity.

THERMOELECTRIC POLYMER AEROGELS AND METHODS OF FABRICATION THEREOF

This disclosure provides systems, methods, and apparatus related to thermoelectric polymer aerogels. In one aspect, a method includes depositing a solution on a substrate. The solution comprises a thermoelectric polymer. Solvent of the solution is removed to form a layer of the thermoelectric polymer. The layer is placed in a polar solvent to form a gel comprising the thermoelectric polymer. The gel is cooled to freeze the polar solvent. The gel is placed in a vacuum environment to sublimate the polar solvent from the gel to form an aerogel comprising the thermoelectric polymer.

DEGRADABLE HEMOSTATIC SPONGE AND PREPARATION METHOD AND USE THEREOF, AND DEGRADABLE DRUG-LOADED HEMOSTATIC SPONGE
20220305169 · 2022-09-29 ·

The present disclosure belongs to the technical field of hemostatic materials, and specifically relates to a degradable hemostatic sponge and a preparation method and use thereof, and a degradable drug-loaded hemostatic sponge. The degradable hemostatic sponge provided by the present disclosure is prepared from raw materials including a crosslinking-modified starch and a cellulose through freeze-drying, where a mass ratio of the crosslinking-modified starch to the cellulose is (0.2-5):1. The degradable hemostatic sponge provided by the present disclosure has a high water-absorbing rate and a large water-absorbing capacity, shows a high support strength and a long support time after water absorption, and is made from plant-derived raw materials and thus may be completely biodegraded. The degradable drug-loaded starch hemostatic sponge provided by the present disclosure has a drug-loaded coating attached to a surface of the sponge, where the drug is slowly released while a support is maintained.

Foam-formed collagen strand

Foam-formed collagen strands and methods for forming strands involve depositing a dispersed solution of an isolated cleaned, de-fatted, enzymatically-treated (or non-enzyme treated) human-derived collagen product having a preserved amount of its natural constituents into grooves of a grooved plate, and processing the dispersed collagen product to provide a foam-formed collagen strand. Foam-formed collagen strands may be processed into threads having a matrix of reticulated pores to conduct biological materials in and through the strand, the collagen of the collagen strand comprising isolated, enzymatically-treated human derived collagen having a preserved amount of its natural collagen constituents.