A method of immobilization of an insoluble dopant. In some embodiments, the insoluble dopant comprises a coordination polymer. In some embodiments, the insoluble dopant comprises a vapochromic coordination polymer. The method may comprise dissolving a polymer carrier in a solvent. The polymer carrier may comprise a thermoplastic such as, but not limited to, polylactic acid, polyethylene glycol or polycarbonate. The insoluble dopant (e.g. a coordination polymer such as a vapochromic coordination polymer) may then be mixed into the dissolved polymer. Phase separation of the mixture of the dopant and dissolved polymer may be induced to form a hydrogel. The hydrogel may be employed as is (e.g. as a raw material for hydrogel 3D printing, as a sensing material, etc.) or may undergo further processing (e.g. solidification, grinding, extrusion, etc.) before being employed, for example, as a raw material for 3D printing, as a sensing material, etc.

The invention provides hydrogel, wherein the hydrogel has a supramolecular cross-linked network obtainable or obtained from the complexation of an aqueous composition including a host, such as cucurbituril, and one or more polymers having suitable guest functionality. One or more polymers in the aqueous composition may have a molecular weight of 50 kDa or more, such as 200 kDa or more. The hydrogel may hold a component, such as a therapeutic compound or a biological molecule. The hydrogels are suitable for use in medicine.

The disclosure relates to compositions and superstructures comprising peptide amphiphiles. In some aspects, the disclosure relates to compositions and superstructures comprising host and guest peptide amphiphiles, wherein the host and guest moieties of the peptide amphiphiles interact via non-covalent interactions to form a supramolecular assembly, such a superstructure. In some aspects, the superstructure further comprises a bioactive moiety. Suitable bioactive moieties may be selected to promote cell growth, migration, and/or differentiation.

A structured organic film (SOF) is disclosed. The structured organic film includes a plurality of segments, a plurality of linkers, and a plurality of capping segments. The structured organic film also includes a first surface of the SOF. The film also includes a parallel second surface of the SOF connected to the first surface by a thickness of the SOF, where a segment to capping segment ratio is greater at the first surface as compared to the parallel second surface. A membrane including a free-standing film comprised of a structured organic film is also disclosed.

The disclosure relates to compositions and superstructures comprising peptide amphiphiles. In some aspects, the disclosure relates to compositions and superstructures comprising host and guest peptide amphiphiles, wherein the host and guest moieties of the peptide amphiphiles interact via non-covalent interactions to form a supramolecular assembly, such a superstructure. In some aspects, the superstructure further comprises a bioactive moiety. Suitable bioactive moieties may be selected to promote cell growth, migration, and/or differentiation.

A method of immobilization of an insoluble dopant. In some embodiments, the insoluble dopant comprises a coordination polymer. In some embodiments, the insoluble dopant comprises a vapochromic coordination polymer. The method may comprise dissolving a polymer carrier in a solvent. The polymer carrier may comprise a thermoplastic such as, but not limited to, polylactic acid, polyethylene glycol or polycarbonate. The insoluble dopant (e.g. a coordination polymer such as a vapochromic coordination polymer) may then be mixed into the dissolved polymer. Phase separation of the mixture of the dopant and dissolved polymer may be induced to form a hydrogel. The hydrogel may be employed as is (e.g. as a raw material for hydrogel 3D printing, as a sensing material, etc.) or may undergo further processing (e.g. solidification, grinding, extrusion, etc.) before being employed, for example, as a raw material for 3D printing, as a sensing material, etc.