Fouling on the surface of biomaterials and medical devices by proteins and microorganisms in the body severely hinders device functionality and drastically shortens lifetime. Currently, there is high demand for coatings that mitigate this biofouling. In this invention, the use of polyacrylamides has been explored in hydrogel coatings by building the largest library of acrylamide-based copolymer anti-biofouling hydrogels (>160 combinations) to date. A combinatorial approach was used, exploiting the ease of hydrogel synthesis to examine a high-throughput screening of platelet adhesion, precursor to thrombosis and a common culprit in biofouling. Applicability has been demonstrated of top-performing polyacrylamide-based hydrogel by (i) coating affinity-based electrochemical biosensors in vitro in a whole blood assay, and (ii) through coating an electrochemical aptamer-based device for real-time monitoring of analytes in an in vivo closed-loop system.

There is provided herein a resin composition comprising:

(i) a silane coupling agent of the general formula (I):

##STR00001##

as described herein, and

(ii) at least one resin which is interactive with one or more of the R.sup.1, R.sup.2 and X groups of silane coupling agent (i).

There is provided herein a resin composition comprising:

(i) a silane coupling agent of the general formula (I):

##STR00001##

as described herein, and

(ii) at least one resin which is interactive with one or more of the R.sup.1, R.sup.2 and X groups of silane coupling agent (i).

The invention provides a composition for forming an easy-to-detach thin resin film, the composition being characterized by including a urethane (meth)acrylate compound, and a first polymerizable composition containing an ethylenic unsaturated monomer having a tert-butoxy group and a radical polymerization initiator, or a polymer of a second polymerizable composition containing the ethylenic unsaturated monomer having a tert-butoxy group, wherein the amount of the ethylenic unsaturated monomer having a tert-butoxy group is 5 mass % or more and less than 95 mass % with respect to the sum of the amount of the urethane (meth)acrylate compound and the total amount of the monomer(s) contained in the first polymerizable composition or the second polymerizable composition.

The invention provides a composition for forming an easy-to-detach thin resin film, the composition being characterized by including a urethane (meth)acrylate compound, and a first polymerizable composition containing an ethylenic unsaturated monomer having a tert-butoxy group and a radical polymerization initiator, or a polymer of a second polymerizable composition containing the ethylenic unsaturated monomer having a tert-butoxy group, wherein the amount of the ethylenic unsaturated monomer having a tert-butoxy group is 5 mass % or more and less than 95 mass % with respect to the sum of the amount of the urethane (meth)acrylate compound and the total amount of the monomer(s) contained in the first polymerizable composition or the second polymerizable composition.

A gas-absorbing material that contains amino group-having polymer compound particles and fine particles having a primary particle diameter of 1000 nm or less is a gas-absorbing material having a markedly higher gas absorption/desorption speed. Here, as the polymer compound of the amino group-having polymer compound particles, for example, a (meth)acrylamide polymer can be used, and as the fine particles, for example, water-repellent inorganic particles or fluororesin particles can be used.

A gas-absorbing material that contains amino group-having polymer compound particles and fine particles having a primary particle diameter of 1000 nm or less is a gas-absorbing material having a markedly higher gas absorption/desorption speed. Here, as the polymer compound of the amino group-having polymer compound particles, for example, a (meth)acrylamide polymer can be used, and as the fine particles, for example, water-repellent inorganic particles or fluororesin particles can be used.

A polymer compound is provided which is changed from a water-insoluble state to a water-soluble state by irradiation with light. The polymer compound is represented by Formula (5), where A and B are a single bond or a functional group, R.sup.3, R.sup.4, and R.sup.9 are hydrogen or an alkyl group, and R.sup.6 and R.sup.7 are hydrogen, an alkyl group, or the like.

A polymer compound is provided which is changed from a water-insoluble state to a water-soluble state by irradiation with light. The polymer compound is represented by Formula (5), where A and B are a single bond or a functional group, R.sup.3, R.sup.4, and R.sup.9 are hydrogen or an alkyl group, and R.sup.6 and R.sup.7 are hydrogen, an alkyl group, or the like.

The present invention provides a method for producing an optical film excellent in anti-fouling properties and scratch resistance as well as anti-reflection properties. The method includes the steps of: (1) applying a lower layer resin and an upper layer resin; (2) forming a resin layer having the uneven structure on a surface thereof by pressing a mold against the lower layer resin and the upper layer resin from the upper layer resin side in the state where the applied lower layer resin and upper layer resin are stacked; and (3) curing the resin layer, the lower layer resin containing at least one kind of first monomer that contains no fluorine atoms, the upper layer resin containing a fluorine-containing monomer and at least one kind of second monomer that contains no fluorine atoms, at least one of the first monomer and the second monomer containing a compatible monomer that is compatible with the fluorine-containing monomer and being dissolved in the lower layer resin and the upper layer resin.