Provided is a chiller and system that may be utilized in a supercritical fluid chromatography method, wherein a non-polar solvent may replace a portion or all of a polar solvent for the purpose of separating or extracting desired sample molecules from a combined sample/solvent stream. The system may reduce the amount of polar solvent necessary for chromatographic separation and/or extraction of desired samples. The system may incorporate a supercritical fluid chiller, a supercritical fluid pressure-equalizing vessel and a supercritical fluid cyclonic separator. The supercritical fluid chiller allows for efficient and consistent pumping of liquid-phase gases employing off-the-shelf HPLC pumps. The pressure equalizing vessel allows the use of off-the-shelf HPLC column cartridges. The system may further incorporate the use of one or more disposable cartridges containing silica gel or other suitable medium. The system may also utilize an open loop cooling circuit using fluids with a positive Joule-Thompson coefficient.

A method for liquefying a natural gas primarily including methane, preferably at least 85% of methane, the other components essentially including nitrogen and C2-C4 alkanes, in which the natural gas to be liquefied is liquefied by circulating at a pressure P0 no lower than the atmospheric pressure (Patm), P0 preferably being higher than the atmospheric pressure, in at least one cryogenic heat-exchanger (EC1, EC2, EC3) by a counter-current closed-circuit circulation in indirect contact with at least one stream of coolant gas remaining in the compressed gaseous state at a pressure P1 that is entering the cryogenic heat-exchanger at a temperature T3′ that is lower than T3, T3 being the liquefaction temperature of the liquefied natural gas at the pressure P0 at the output of said cryogenic exchanger, characterized in that the coolant gas includes a mixture of nitrogen and at least one other component selected from among neon and hydrogen.

Provided is a chiller and system that may be utilized in a supercritical fluid chromatography method, wherein a non-polar solvent may replace a portion or all of a polar solvent for the purpose of separating or extracting desired sample molecules from a combined sample/solvent stream. The system may reduce the amount of polar solvent necessary for chromatographic separation and/or extraction of desired samples. The system may incorporate a supercritical fluid chiller, a supercritical fluid pressure-equalizing vessel and a supercritical fluid cyclonic separator. The supercritical fluid chiller allows for efficient and consistent pumping of liquid-phase gases employing off-the-shelf HPLC pumps. The pressure equalizing vessel allows the use of off-the-shelf HPLC column cartridges. The system may further incorporate the use of one or more disposable cartridges containing silica gel or other suitable medium. The system may also utilize an open loop cooling circuit using fluids with a positive Joule-Thomson coefficient.

A working fluid for a heat cycle, contains: trifluoroethylene; and a first component consisting of at least one of substance selected from carbon dioxide, fluoromethane, trifluoroiodomethane, methane, ethane, propane, helium, neon, argon, krypton, xenon, nitrogen and ammonia.

The present invention relates to a refrigerant composition. According to the invention it is envisioned that the composition comprises comprising an inert gas selected from nitrogen, argon, neon and a mixture thereof, and a mixture of at least two C.sub.1-C.sub.5 hydrocarbons. The present invention further relates to the use of the refrigerant composition in a method for liquefying a gaseous substance, particularly hydrogen or helium.

An object of the present disclosure is to provide a composition with a limited polymerization of a refrigerant, a storage method, and a polymerization inhibition method. The composition contains (1) a refrigerant and (2) oxygen, wherein the concentration of the oxygen (2) is 1 ppm or more by volume at a temperature of 25° C.

Provided is a chiller and system that may be utilized in a supercritical fluid chromatography method, wherein a non-polar solvent may replace a portion or all of a polar solvent for the purpose of separating or extracting desired sample molecules from a combined sample/solvent stream. The system may reduce the amount of polar solvent necessary for chromatographic separation and/or extraction of desired samples. The system may incorporate a supercritical fluid chiller, a supercritical fluid pressure-equalizing vessel and a supercritical fluid cyclonic separator. The supercritical fluid chiller allows for efficient and consistent pumping of liquid-phase gases employing off-the-shelf HPLC pumps. The pressure equalizing vessel allows the use of off-the-shelf HPLC column cartridges. The system may further incorporate the use of one or more disposable cartridges containing silica gel or other suitable medium. The system may also utilize an open loop cooling circuit using fluids with a positive Joule-Thompson coefficient.

The embodiments of the invention disclose a mixed refrigerant for a cryogenic temperature range, and methods for preparing and applying the same. The mixed refrigerant comprises six types of refrigerants: the first type of refrigerant is argon or nitrogen; the second type of refrigerant is methane or krypton; the third type of refrigerant is tetrafluoromethane; the fourth type of refrigerant is trifluoromethane or fluoromethane; the fifth type of refrigerant is at least one of 2,3,3,3□tetrafluoro-1-propene, hexafluoropropylene, pentafluoropropene, and 1,3,3,3-tetrafluoro-1-propene; and the sixth type of refrigerant is at least one of 1,1,1,3,3-pentafluoropropane, 1,1,2,2,3-pentafluoropropane, monochloro-trifluoropropene, and hexafluoro-2-butene. The mixed refrigerant has the advantages of a low ODP value, a low GWP value and non-flammability, it achieves the beneficial effects of non-toxic, environmental-friendly, convenient and safe, and it is for large-scale industrial production applications.

Provided is a chiller and system that may be utilized in a supercritical fluid chromatography method, wherein a non-polar solvent may replace a portion or all of a polar solvent for the purpose of separating or extracting desired sample molecules from a combined sample/solvent stream. The system may reduce the amount of polar solvent necessary for chromatographic separation and/or extraction of desired samples. The system may incorporate a supercritical fluid chiller, a supercritical fluid pressure-equalizing vessel and a supercritical fluid cyclonic separator. The supercritical fluid chiller allows for efficient and consistent pumping of liquid-phase gases employing off-the-shelf HPLC pumps. The pressure equalizing vessel allows the use of off-the-shelf HPLC column cartridges. The system may further incorporate the use of one or more disposable cartridges containing silica gel or other suitable medium. The system may also utilize an open loop cooling circuit using fluids with a positive Joule-Thompson coefficient.

A test chamber (10) for conditioning air has a test space (12), and a temperature control device (11) for controlling the temperature of the test space and allowing a temperature in a range of 80 C. to +180 C., preferably 100 C. to +200 C., to be established within the test space, the temperature control device having a cooling device (16) with a cooling circuit (17), a heat exchanger (18), a compressor (19), a condenser (20), and an expansion element (21), wherein the refrigerant is a nearly azeotropic and/or zeotropic refrigerant mixture of a mass percentage of carbon dioxide and a mass percentage of at least one of the components ethane, ethene, hexafluoroethane, pentafluoroethane, monofluoro-ethane, 1,1-difluoroethene, fluoromethane and/or propane and/or xenon, the refrigerant having a relative CO2 equivalent of <3000, preferably <500, in particular preferably <10, with respect to 20 years.