A method for improving a biogas production is provided in which an organic substrate is pretreated by various methods. In particular, the method includes a combination of a magnetic and an enzymatic pretreatment of the substrate with an attractive specific energy gain. The application of a magnetic field induces changes in biological systems

Disclosed herein are cell processing systems, devices, and methods thereof. A system for cell processing may comprise a plurality of instruments each independently configured to perform one or more cell processing operations upon a cartridge, and a robot capable of moving the cartridge between each of the plurality of instruments.

Magnetic-based actuation mechanisms for and methods of actuating magnetically-responsive microposts in a reaction (or assay) chamber is disclosed. For example, a microfluidics system is provided that includes a microfluidics device (or cartridge) that includes the reaction (or assay) chamber in which a field of magnetically-responsive surface-attached microposts is installed. The presently disclosed magnetic-based actuation mechanisms are provided in close proximity to the magnetically-responsive microposts wherein the magnetic-based actuation mechanisms are used for actuating the magnetically-responsive microposts. For example, the magnetic-based actuation mechanisms generate an actuation force that is used to induce, for example, synchronized beat patterns and/or metachronal beat patterns in the magnetically-responsive microposts. Additionally, a method of using the presently disclosed magnetic-based actuation mechanisms for actuating the magnetically-responsive microposts is provided.

A magnetic cell biocarrier combined with a powerless bioreactor system comprising a biocarrier, a powerless bioreactor, and a magnetic field device. The biocarrier can detach the cells through temperature regulation and can be adsorbed by the magnetic field device to stabilize at the bottom of the gooseneck cell culture tank; the powerless bioreactor comprises a microinfusion element, a culture fluid collection element, and a gooseneck cell culture tank; the internal space of the gooseneck cell culture tank is interconnected with the microinfusion element and the culture fluid collection element, the microinfusion element slowly injects fresh culture medium When the culture medium in the gooseneck cell culture tank is above an overflow position, the cell metabolites can be automatically discharged to the culture fluid collection element by the interconnected vessels to reduce the risk of cell contamination.

Certain examples of the disclosure concern an apparatus including a microcarrier configured to receive and support attachment and growth of cells, and a magnetoelastic sensor enclosed by the microcarrier. The magnetoelastic sensor is configured to vibrate in response to an activation magnetic field, and the vibration can produce a return magnetic field having detectable field characteristics associated with the attachment or growth of the cells.

Disclosed is a device for mechanically characterizing an element of interest, for example an oocyte. The mechanical characterization device includes: a support receiving a container suitable for containing a liquid medium; a holder for holding the element of interest; an indenting member; a magnet for generating a magnetic field in which the indenting member is intended to move and which participates in suspending the indenting member with an unstable horizontal direction oriented coaxially to the longitudinal axis; a controller to control the magnet to maneuver the indenting member in translation along the unstable horizontal direction; and a component for determining the mechanical characteristics of the element of interest.

A magnetic-field generator (10) is provided to be used in construction of a cell sheet (12), and include s a magnetic circuit assembly (24) configured to generate a magnetic field for the construction of the cell sheet (12) using magnetic force caused by the magnetic field wherein the magnetic force is substantially transverse to a plane defined by the cell sheet (12), and a power control system (44) configured to generate and control electric power to magnetically charge the magnetic circuit assembly (24) using the electric power.

The present invention relates to a device (1) for treating cells for stimulating cell growth, comprising a unit (2) for generating and emitting electric pulses, and a treatment unit (3) having an inlet (3a) and an outlet (3a), a treatment space (4) being formed inside the treatment unit (3), the treatment space (4) being penetrated by the emitted electric pulses and an electric field resulting therefrom, a cell material entering into the treatment space (4) through the inlet (3a) being moved without contact through the treatment space (4) and the electric field penetrating the treatment space (4) to the outlet (3b).

Systems, methods, and devices for culturing a multicellular structure, such as an organoid. An exemplary system comprises a vessel, an electric/magnetic module, and a control circuit. The vessel may include a culture chamber to contain a multicellular structure. The electric/magnetic module may be configured to be located in the vessel, at a position in or adjacent the culture chamber. The control circuit may be configured to wirelessly power and/or operate the electric/magnetic module.

An incubator-actuator device including a sample chamber, a magnetic field generating coil, and a light-emitting diode (LED) placement cage is provided herein. The incubator-actuator device is configured for simultaneous optical irradiation and oscillating magnetic field irradiation of a mammalian cell or a nanostructure. A system including an incubator-actuator device including a sample chamber, a magnetic field generating coil, and a light-emitting diode (LED) placement cage, and a laser is also provided herein. The system is configured for simultaneous optical irradiation and oscillating magnetic field irradiation of a target.