Patent classifications
C
C12
C12N
2740/00
C12N2740/00011
C12N2740/00033
C12N2740/00033
RETROVIRAL VECTOR FOR UNIVERAL RECEPTOR THERAPY
The present disclosure relates to retroviral vectors comprising polynucleotides encoding hapten-binding receptors and T cell activating receptors. The retroviral vectors may also comprise transduction enhancers. Also disclosed are adaptor molecules and their use in conjunction with the retroviral vectors and T cells transduced with the retroviral vectors.