C12N2740/00033

RETROVIRAL VECTOR FOR UNIVERAL RECEPTOR THERAPY
20240122978 · 2024-04-18 ·

The present disclosure relates to retroviral vectors comprising polynucleotides encoding hapten-binding receptors and T cell activating receptors. The retroviral vectors may also comprise transduction enhancers. Also disclosed are adaptor molecules and their use in conjunction with the retroviral vectors and T cells transduced with the retroviral vectors.