An inactivated influenza vaccine may have high immunogenicity and may be produced by method including performing inactivation treatment using formaldehyde including treating a virus solution containing an influenza virus collected from a host with β-propiolactone in advance. The inactivation treatment using formaldehyde may be performed by adding formalin to the virus solution at a final concentration of 0.005 to 0.015 vol %.

The present disclosure features methods and compositions for enhancing the ability of the respiratory membranes to filter airborne pathogens and protect a subject from respiratory infections that result from inhalation or ingestion of such pathogens. In particular, the disclosure provides antimicrobial compositions that prevent and treat respiratory infections caused by bacteria, fungi, and viruses.

The present disclosure features methods and compositions for enhancing the ability of the respiratory membranes to filter airborne pathogens and protect a subject from respiratory infections that result from inhalation or ingestion of such pathogens. In particular, the disclosure provides antimicrobial compositions that prevent and treat respiratory infections caused by bacteria, fungi, and viruses.

The invention is directed to compositions and methods for collecting, transporting, and storing, preferably without refrigeration, biological materials, which may comprise samples of biological, clinical, forensic, and/or environmental origin. Compositions preserve the fidelity and/or viability of the collected organisms and/or macromolecules in the sample and permit long-term storage. Compositions are compatible with manipulation of the sample, including propagation and culture of the microorganisms, or isolation, purification, detection, and characterization of macromolecules. Compositions containing microorganisms or macromolecules can be further processed, for example, by nucleic acid testing with greater fidelity and detection as compared to conventional microbial transport media. In particular, the compositions disclosed allow for the safe collection, transport and storage of biological samples for extended periods at ambient temperature, while maintaining the integrity of the macromolecules of the sample for subsequent extraction, identification, and quantitation.

An influenza vaccine that has high immunogenicity in children and elderly people and has a higher efficacy than conventional split vaccines. An influenza vaccine composition to be administered to children and/or elderly people, including, as a virus antigen, inactivated whole particles subjected to inactivation treatment with beta-propiolactone.

The invention is directed to compositions and methods for collecting, transporting, and storing, preferably without refrigeration, biological materials, which may comprise samples of biological, clinical, forensic, and/or environmental origin. Compositions preserve the fidelity and/or viability of the collected organisms and/or macromolecules in the sample and permit long-term storage. Compositions are compatible with manipulation of the sample, including propagation and culture of the microorganisms, or isolation, purification, detection, and characterization of macromolecules. Compositions containing microorganisms or macromolecules can be further processed, for example, by nucleic acid testing with greater fidelity and detection as compared to conventional microbial transport media. In particular, the compositions disclosed allow for the safe collection, transport and storage of biological samples for extended periods at ambient temperature, while maintaining the integrity of the macromolecules of the sample for subsequent extraction, identification, and quantitation.

The present disclosure features methods and compositions for enhancing the ability of the respiratory membranes to filter airborne pathogens and protect a subject from respiratory infections that result from inhalation or ingestion of such pathogens. In particular, the disclosure provides antimicrobial compositions that prevent and treat respiratory infections caused by bacteria, fungi, and viruses.

The present disclosure features methods and compositions for enhancing the ability of the respiratory membranes to filter airborne pathogens and protect a subject from respiratory infections that result from inhalation or ingestion of such pathogens. In particular, the disclosure provides antimicrobial compositions that prevent and treat respiratory infections caused by bacteria, fungi, and viruses.