Patent classifications
C
CHEMISTRY; METALLURGY
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C12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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C12N
MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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C12N2770/32351
Methods of production or purification of viral material
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C12N2770/32352
relating to complementing cells and packaging systems for producing virus or viral particles
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C12N2770/32352

Engineered cells with decreased gene expression resulting in increased viral production
11655471 · 2023-05-23 · ·

Disclosed are compositions and methods for increasing virus production. In particular, disclosed herein are cell or cell line comprises reduced expression of one or more cellular genes selected from the group comprising COQ9, FGF2, NAT9, NDUFA9, NEU2, PLA2G1B, PYCR1, RAD51AP1, STRADA, SVOPL, and/or ZFYVE9 for use in increasing viral production.

METHODS AND COMPOSITIONS RELATED TO INCREASED VIRAL PRODUCTION
20200010830 · 2020-01-09 ·

Disclosed are compositions and methods for increasing virus production.