Patent classifications
C12P13/16
Noscapinoid-producing Microbes and Methods of Making and Using the Same
Engineered non-plant cells that produce a benzylisoquinoline alkaloid product that is a derivative of canadine along a metabolic pathway that converts canadine, or an analog of canadine, to a noscapinoid product are provided. Methods of culturing engineered non-plant cells that produce a noscapinoid product and pharmaceutical compositions are also provided.
Noscapinoid-producing Microbes and Methods of Making and Using the Same
Engineered non-plant cells that produce a benzylisoquinoline alkaloid product that is a derivative of canadine along a metabolic pathway that converts canadine, or an analog of canadine, to a noscapinoid product are provided. Methods of culturing engineered non-plant cells that produce a noscapinoid product and pharmaceutical compositions are also provided.
NOSCAPINOID-PRODUCING MICROBES AND METHODS OF MAKING AND USING THE SAME
Engineered non-plant cells that produce a benzylisoquinoline alkaloid product that is a derivative of canadine along a metabolic pathway that converts canadine, or an analog of canadine, to a noscapinoid product are provided. Methods of culturing engineered non-plant cells that produce a noscapinoid product and pharmaceutical compositions are also provided.
NOSCAPINOID-PRODUCING MICROBES AND METHODS OF MAKING AND USING THE SAME
Engineered non-plant cells that produce a benzylisoquinoline alkaloid product that is a derivative of canadine along a metabolic pathway that converts canadine, or an analog of canadine, to a noscapinoid product are provided. Methods of culturing engineered non-plant cells that produce a noscapinoid product and pharmaceutical compositions are also provided.
ACYL AMINO ACID PRODUCTION
The present invention relates to a microbial cell for producing at least one acyl amino acid, wherein the cell is genetically modified to comprise; a first genetic mutation that enables the cell to produce at least one acyl amino acid and; a second genetic mutation that enables the cell to decrease glutamate breakdown relative to the wild type cell.
ACYL AMINO ACID PRODUCTION
The present invention relates to a microbial cell for producing at least one acyl amino acid, wherein the cell is genetically modified to comprise; a first genetic mutation that enables the cell to produce at least one acyl amino acid and; a second genetic mutation that enables the cell to decrease glutamate breakdown relative to the wild type cell.