Provided herein are Metschnikowia species that produce xylitol from xylose when cultured, as well as methods to make and use these Metschnikowia species.

Provided herein are Metschnikowia species that produce xylitol from xylose when cultured, as well as methods to make and use these Metschnikowia species.

The present disclosure provides recombinant microorganisms capable of sugar co-utilization, the recombinant microorganism comprising a genetically altered microorganism (e.g. S. cerevisiae) having a lack of, or reduced expression of, or expression of truncated or mutated forms of at least one polypeptide selected from Hxk1, Hxk2, and Glk1. Reduction of the expression or biological activity of Hxk1, Hxk2 and Glk1 leads to reduction in the glucose consumption pathway, allowing the microorganism to co-utilize multiple sugars (e.g. glucose, xylose, galactose) at an improved rate.

Provided herein are Metschnikowia species that produce xylitol from xylose when cultured, as well as methods to make and use these Metschnikowia species.

The present invention relates to a recombinant microorganism having the ability to produce poly(lactate-co-glycolate) and its copolymers from xylose, and more particularly to a recombinant microorganism having the ability to produce poly(lactate-co-glycolate) and its copolymers without having to supply a glycolate precursor from an external source, and a method of producing a poly(lactate-co-glycolate) copolymers using the same.

Provided herein are Metschnikowia species that produce xylitol from xylose when cultured, as well as methods to make and use these Metschnikowia species.

The present invention relates to a recombinant microorganism having the ability to produce poly(lactate-co-glycolate) and its copolymers from xylose, and more particularly to a recombinant microorganism having the ability to produce poly(lactate-co-glycolate) and its copolymers without having to supply a glycolate precursor from an external source, and a method of producing a poly(lactate-co-glycolate) copolymers using the same.

Provided herein are Metschnikowia species that produce xylitol from xylose when cultured, as well as methods to make and use these Metschnikowia species.