The present disclosure relates to an artificial metabolon formed by selective self-assembly, production and use thereof, specifically, an artificial metabolon formed by de novo, in vivo assembly of multi-step metabolic pathway enzymes without using any external scaffold, production and use thereof.

The present invention relates to a recombinant microorganism which is modified to be capable of producing diosmin and hesperidin and to the use thereof for producing diosmin and/or hesperidin.

Provided is: a transgenic plant that has a modified flower color; a self- or cross-fertilized descendant of the transgenic plant; or a propagule, a portion of a plant body, tissue, or cells from the transgenic plant or the self- or cross-fertilized descendant of the transgenic plant. The present invention causes both anthocyanin delphinidin and a flavone C-glycoside that is methylated at the hydroxyl group at the 7 position to be present in the cells of a plant.

Transgenic plants with modified flower color, or their inbred or outbred progeny, or their propagates, partial plant bodies, tissues or cells, are provided. A delphinidin-type anthocyanin and a flavone C-glycoside in which the 7-position and T-position hydroxyl groups are methylated, are caused to coexist in plant cells.

Provided are a transformed plant having a blue-hued flower color or its inbred or outbred progenies, or their propagules, partial plant bodies, tissues or cells.

Delphinidin type anthocyanin and flavone C-glycoside are made to be coexpressed in petals.

The present invention relates to a recombinant microorganism which is modified to be capable of producing diosmin and hesperidin and to the use thereof for producing diosmin and/or hesperidin.

The present invention relates to a recombinant microbial host cell producing a tetraketide or derivatives thereof from one or more substrates selected from cinnamoyl-CoA, p-Coumaroyl-CoA, Caffeoyl-CoA, Feruloyl-CoA, malonyl-CoA, sinapoyl-CoA and dihydro derivatives thereof, comprising an operative biosynthetic metabolic pathway for the tetraketide or derivatives thereof comprising a chalcone isomerase-like (CHIL) polypeptide heterologous to the host cell and a Type 3 polyketide synthase (PKS).

Disclosed are methods for producing butadiene from one or more of several diverse feedstocks including bioderived feedstocks, renewable feedstocks, petrochemical feedstocks and natural gas.

The present invention relates to a recombinant microorganism which is modified to be capable of producing diosmin and hesperidin and to the use thereof for producing diosmin and/or hesperidin.

Disclosed are methods for producing butadiene from one or more of several diverse feedstocks including bioderived feedstocks, renewable feedstocks, petrochemical feedstocks and natural gas.