Patent classifications
C
CHEMISTRY; METALLURGY
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C12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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C12Y
ENZYMES
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114/00
Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
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C12Y114/12
with NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor (1.14.12)
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C12Y114/12013
2-Halobenzoate 1,2-dioxygenase (1.14.12.13)
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C12Y114/12013

USE OF TYPE I AND TYPE II POLYKETIDE SYNTHASES FOR THE PRODUCTION OF CANNABINOIDS AND CANNABINOID ANALOGS
20210403959 · 2021-12-30 ·

The present invention relates generally to production methods, enzymes and recombinant yeast strains for the biosynthesis of clinically important prenylated polyketides of the cannabinoid family. Using readily available starting materials, heterologous enzymes are used to direct cannabinoid biosynthesis in yeast.