C12Y303/02006

Multiple proteases deficient filamentous fungal cells and methods of use thereof

The present disclosure relates to compositions and methods useful for the production of heterologous proteins in filamentous fungal cells.

Multiple Proteases Deficient Filamentous Fungal Cells and Methods of Use Thereof

The present disclosure relates to compositions and methods useful for the production of heterologous proteins in filamentous fungal cells.

Multiple proteases deficient filamentous fungal cells and methods of use thereof

The present disclosure relates to compositions and methods useful for the production of heterologous proteins in filamentous fungal cells.

Multiple Proteases Deficient Filamentous Fungal Cells and Methods of Use Thereof

The present disclosure relates to compositions and methods useful for the production of heterologous proteins in filamentous fungal cells.

Multiple protease deficient filamentous fungal cells and methods of use thereof

The present disclosure relates to compositions and methods useful for the production of heterologous proteins in filamentous fungal cells.

Multiple Protease Deficient Filamentous Fungal Cells and Methods of Use Thereof

The present disclosure relates to compositions and methods useful for the production of heterologous proteins in filamentous fungal cells.

Multiple proteases deficient filamentous fungal cells and methods of use thereof

The present disclosure relates to compositions and methods useful for the production of heterologous proteins in filamentous fungal cells.

LEUKOTRIENE A4 HYDROLASE (LTA4H) AS (BLOOD) BIOMARKER FOR THE DIAGNOSIS OF POLYCYSTIC OVARIAN SYNDROME

The present invention relates to a method for assessing whether a subject has Polycystic Ovarian Syndrome (PCOS) or is at risk of developing PCOS, to a method of selecting a patient for therapy of PCOS, to a method for monitoring PCOS progression or for monitoring response to treatment and to a computer-implemented method for assessing a subject with suspected PCOS, by determining the amount or concentration of Leukotriene A4 Hydrolase (LTA4H) in a sample of the subject.

RATIO BETWEEN LTA4H AND METRNL IN THE ASSESSMENT OF POLYCYSTIC OVARIAN SYNDROME

The present invention relates to a method for diagnosing Polycystic Ovarian Syndrome (PCOS) in a subject, said method comprising the steps of a) determining the amount or concentration of total LTA4H in sample from the subject, b) determining the amount or concentration of METRNL in a sample from the subject, c) calculating a score of the amounts or concentration determined in steps a) and b), d) comparing the calculated score with a reference score, and e) diagnosing PCOS in a subject.