The invention relates to truncated growth factors and variants thereof. The invention also relates to methods of making and using the truncated growth factors. The invention further relates to compositions including a protease and a growth factor comprising a bone morphogenic protein (BMP) or a variant thereof. The invention also relates to methods of using the composition.

The present invention relates to the field of use of animal cells for producing products containing animal-derived materials in a sustainable manner, preserving natural resources and promoting animal welfare, particularly for production of cell-free collagen and use thereof for forming textile, particularly leather-like textile, food products, particularly cultured meat, cosmetic products, and medical uses.

The invention relates to truncated growth factors and variants thereof. The invention also relates to methods of making and using the truncated growth factors. The invention further relates to compositions including a protease and a growth factor comprising a bone morphogenic protein (BMP) or a variant thereof. The invention also relates to methods of using the composition.