C12Y305/99

Reducing the accumulation of imines/enamines for the production of amino acids or amino acid-derived products

Provided microorganisms genetically modified to overexpress an imine/enamine deaminase to enhance the production of lysine and lysine derivatives by the microorganism. Also provided a method of generating such microorganism, and methods of producing lysine and lysine derivatives using the genetically modified microorganisms.

REDUCING THE ACCUMULATION OF IMINES/ENAMINES FOR THE PRODUCTION OF AMINO ACIDS OR AMINO ACID-DERIVED PRODUCTS

Provided microorganisms genetically modified to overexpress an imine/enamine deaminase to enhance the production of lysine and lysine derivatives by the microorganism. Also provided a method of generating such microorganism, and methods of producing lysine and lysine derivatives using the genetically modified microorganisms.