The present disclosure provides microbial cells and methods of producing FOPPA resulting from unique biosynthetic pathways, including biosynthetic pathways based on the phenylalanine/tyrosine biosynthetic branch and biosynthetic pathways based on bacteria metabolism. In particular, the present invention provides methods of producing FOPPA in microbial cells. These methods provide a low-cost, sustainable, and environmentally friendly source for FOPPA.

Processes for production of phloroglucinol or derivative thereof. An aspect of the present disclosure relates to an enzymatic process for production of phloroglucinol or derivative thereof from polyphenol. The present disclosure also relates to a process for production of phenolic derivatives. Accordingly, another aspect of the present disclosure relates to an enzymatic process for production of phenolic derivatives from polyphenol. The processes of the present disclosure affords facile and environment friendly production of phloroglucinol or derivative(s) thereof and/or phenolic derivative(s).