C12Y402/01035

PRODUCTION OF L-2-AMINOBUTYRATE FROM CITRAMALATE,CITRACONATE OR 2-OXOBUTANOATE

The present invention relates to preparation of key drug intermediate, L-2-amino butyric acid (L-2-ABA) by a method of cell free system and biotransformation using genetically engineered strains from easily available economic substrates like citramalate or citraconate and enzymes like LeuCD, LeuB and ValDH or IlvE.

Production of L-2-aminobutyrate from citramalate, citraconate or 2-oxobutanoate

The present invention relates to preparation of key drug intermediate, L-2-amino butyric acid (L-2-ABA) by a method of cell free system and biotransformation using genetically engineered strains from easily available economic substrates like citramalate or citraconate and enzymes like LeuCD, LeuB and ValDH or IlvE.