Patent classifications
C
CHEMISTRY; METALLURGY
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C12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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C12Y
ENZYMES
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C12Y501/02
acting on hydroxy acids and derivatives (5.1.2)
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C12Y501/02002
Mandelate racemase (5.1.2.2)
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C12Y501/02002

Method for producing meso-galactaric acid by contacting a fungal cell with a biomaterial having galacturonic acid
10982239 · 2021-04-20 · ·

The present invention relates to a field of genetically modified fungal cells and converting galacturonic acid to meso-galactaric acid, more precisely to a method of producing meso-galactaric acid. The invention further relates to recombinant fungal cells having a specific combination of modifications including but not limited to expression of uronate dehydrogenase enzyme, reduced D-galacturonic acid reductase activity, and furthermore reduced meso-galactaric acid catabolism, as well as uses and methods related thereto.

IMPROVED MESO-GALACTARIC ACID PRODUCTION FROM GALACTURONIC ACID WITH GENETICALLY MODIFIED FUNGAL CELLS
20190256875 · 2019-08-22 ·

The present invention relates to a field of genetically modified fungal cells and converting galacturonic acid to meso-galactaric acid, more precisely to a method of producing meso-galactaric acid. The invention further relates to recombinant fungal cells having a specific combination of modifications including but not limited to expression of uronate dehydrogenase enzyme, reduced D-galacturonic acid reductase activity, and furthermore reduced meso-galactaric acid catabolism, as well as uses and methods related thereto.