Patent classifications
C
CHEMISTRY; METALLURGY
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C12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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C12Y
ENZYMES
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603/00
Ligases forming carbon-nitrogen bonds (6.3)
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C12Y603/02
Acid—amino-acid ligases (peptide synthases)(6.3.2)
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C12Y603/02025
Tubulin-tyrosine ligase (6.3.2.25)
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C12Y603/02025

Unusual substrates of tubulin tyrosine ligase
11572384 · 2023-02-07 · ·

The present invention provides means and methods for functionalizing a polypeptide of interest at its C-terminus with an amino acid derivative.

COMPOSITION AND METHODS FOR IMPROVING HEART FUNCTION AND TREATING HEART FAILURE
20230140435 · 2023-05-04 ·

A recombinant viral vector comprising an expression cassette which comprises a coding sequence for an shRNA inhibitor of vasohibin (VASH)-small vasohibin binding protein (SVBP) complex operably linked to regulatory sequences which direct expression thereof is provided. Further provided are compositions containing such viral vectors formulated for delivery to a human patient. Also provided are methods using these vectors and compositions for improving or stabilizing cardiac function.

MEANS AND METHODS FOR SITE-SPECIFIC FUNCTIONALIZATION OF POLYPEPTIDES
20170349625 · 2017-12-07 ·

The present invention provides means and methods for equipping a polypeptide of interest at its C-terminus with a versatile adaptor amino acid that allows the functionalization of the polypeptide of interest.

MEANS AND METHODS FOR SITE-SPECIFIC FUNCTIONALIZATION OF POLYPEPTIDES
20220363714 · 2022-11-17 ·

The present invention provides means and methods for equipping a polypeptide of interest at its C-terminus with a versatile adaptor amino acid that allows the functionalization of the polypeptide of interest.

Means and methods for site-specific functionalization of polypeptides
11401298 · 2022-08-02 · ·

The present invention provides means and methods for equipping a polypeptide of interest at its C-terminus with a versatile adaptor amino acid that allows the functionalization of the polypeptide of interest.

MEANS AND METHODS FOR SITE-SPECIFIC FUNCTIONALIZATION OF POLYPEPTIDES
20210040145 · 2021-02-11 ·

The present invention provides means and methods for equipping a polypeptide of interest at its C-terminus with a versatile adaptor amino acid that allows the functionalization of the polypeptide of interest.

Means and methods for site-specific functionalization of polypeptides
10745437 · 2020-08-18 · ·

The present invention provides means and methods for equipping a polypeptide of interest at its C-terminus with a versatile adaptor amino acid that allows the functionalization of the polypeptide of interest.

MEANS AND METHODS FOR SITE-SPECIFIC FUNCTIONALIZATION OF POLYPEPTIDES
20190337977 · 2019-11-07 ·

The present invention provides means and methods for equipping a polypeptide of interest at its C-terminus with a versatile adaptor amino acid that allows the functionalization of the polypeptide of interest.

Means and methods for site-specific functionalization of polypeptides
11958880 · 2024-04-16 · ·

The present invention provides means and methods for equipping a polypeptide of interest at its C-terminus with a versatile adaptor amino acid that allows the functionalization of the polypeptide of interest.

UNUSUAL SUBSTRATES OF TUBULIN TYROSINE LIGASE
20190144493 · 2019-05-16 ·

The present invention provides means and methods for functionalizing a polypeptide of interest at its C-terminus with an amino acid derivative.