Patent classifications
C
CHEMISTRY; METALLURGY
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C12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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C12Y
ENZYMES
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603/00
Ligases forming carbon-nitrogen bonds (6.3)
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C12Y603/04
Other carbon-nitrogen ligases (6.3.4)
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C12Y603/0402
7-Cyano-7-deazaguanine synthase (6.3.4.20)
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C12Y603/0402

MATERIALS AND METHODS FOR REDUCING NUCLEIC ACID DEGRADATION IN BACTERIA
20220145308 · 2022-05-12 ·

The present disclosure is directed to materials and methods for reducing heterologous DNA damage in bacteria (i.e., induce resistance to host restriction enzymes) by modifying the heterologous DNA to include one or more deazapurine bases.