Electrospinning (ES) provides the technical community with a readily available method to produce polymer fibers ranging from nanoscale to microscale. Here, we present a novel “hybrid electrospirming apparatus,” whereby, modifications to a melt electrospinner have allowed fabrication of core-sheath fibers with polymer sheaths and solution-based cores. These modifications include a split polymer melt heating block, coaxial block spinneret equipped with heaters and multiple feed ports for core and sheath material, and a wiring system for heat which requires multiple switches for safety and on-demand heat activation. Successful demonstration of coaxial fiber fabrication is demonstrated using polycaprolactone-polyethylene oxide blend shell and fluorescent gelatin core materials.

A staple cartridge assembly for use with a surgical stapling instrument includes a staple cartridge including a plurality of staples and a cartridge deck. The staple cartridge assembly also includes a compressible adjunct positionable against the cartridge deck, wherein the staples are deployable into tissue captured against the compressible adjunct, and wherein the compressible adjunct comprises a first biocompatible layer comprising a first portion, a second biocompatible layer comprising a second portion, and crossed spacer fibers extending between the first portion and the second portion.

An electrospinning device includes: a plurality of nozzles that discharge a spinning solution containing a resin; and a plurality of power sources for applying charge to the solution. The power sources are connected such that different charges are applied to the solutions discharged from the nozzles, respectively. The fiber sheet is a long fiber nonwoven fabric including first fibers and second fibers that are different from the first fibers. In a histogram based on fiber diameter distributions and frequencies of the numbers of fibers, the fiber sheet has a peak where a ratio P1 of a frequency of the number of fibers of the first fibers to a frequency of the number of fibers of the second fibers is 0.01 or more and 100 or less. Alternatively, the fiber sheet has two or more peaks in the histogram, in which a ratio P2 of a frequency of the number of fibers of the first fibers at a highest peak in a range of a fiber diameter of 3 μm or less to a frequency of the number of fibers of the second fibers at a highest peak in a range of a fiber diameter of more than 3 μm is 1 or more and 1 000 or less.

Methods for forming an implantable layer onto a staple cartridge are disclosed.

An electrospinning apparatus and method for producing three-dimensional electrospun constructs is disclosed. Further, electrospinning apparatus and method 3D electrospun collagen based mineralized nanofibrous scaffold for alveolar ridge preservation prior to dental implant therapy are disclosed.

The invention relates to a system for manufacturing by electrospinning a composite fibre structure; wherein the system comprises a first device of solution electrospinning comprising a first head biased to a first voltage, a second device of melt electrospinning comprising a second head electrically connected to ground, and a moveable collector configured to be either electrically connected to ground or biased to a second voltage. Wherein the system further comprises switching means configured to selectively assign the electrical status of the collector.

The present disclosure relates to polymer resins, fibers, and yarns with permanent antimicrobial activity, and a method of producing the same. In one embodiment, the antimicrobial polymer resin comprises a polymer having less than 2500 ppm of zinc dispersed within the polymer, less than 1000 ppm of phosphorus, wherein the weight ratio of zinc to phosphorus is at least 1.3:1 or less than 0.64:1.

The invention relates to a process for manufacturing a multilayer knitted textile by heating a multi-layer knitted textile in the presence of one or more dye compounds, wherein the multilayer knitted textile comprises a fabric outer layer and a fabric inner layer, wherein the fabric outer layer is knit from a first yarn containing a combination of modacrylic fibers and cotton fibers, wherein the fabric inner layer is knit from a second yarn made from 50-90% HBA/HNA filaments, wherein the heating shrinks the outer layer from about 5 to 25% in length, width, or both.

A polymeric article of high ductility produced by rapid prototyping or selective laser sintering, and a method of making the same. The article comprises a plurality of layers of a fused thermoplastic powder, the thermoplastic powder comprising asymmetric fibrous particles having a mean length L and a mean width W, wherein L>2 W. Within each of the layers, the mean length L of the asymmetric fibrous particles is preferentially oriented in a plane parallel to the layer. The polymeric article has a stress-strain curve such that ultimate strength is reached at a strain of 10% to 20%, and breaking stress is reached at >30% strain.

The present invention relates to thin filters comprising melt electro spinning writing (MEW) fibers for capturing and culturing circulating tumor cells (CTCs). The invention further relates to processes for producing the filters, methods for capturing and culturing CTCs using the filters, kits and devices comprising the filters and uses of the filters.