According to one embodiment, an electrospinning apparatus deposits a fiber on an electrode. The apparatus includes a transport section and a fiber deposition section. The transport section transports electrodes. The fiber deposition section deposits the fiber on first and second surfaces of the electrodes. The electrodes include coated and uncoated portions. The transport section transports the electrodes in a third direction in the fiber deposition section. The electrodes include first and second electrodes. The first electrode is positioned at one end in the second direction and transported so that the uncoated portion of the first electrode protrudes toward the one end side. The second electrode is positioned at other end in the second direction and transported so that the uncoated portion of the second electrode protrudes toward the other end side.

A functionally gradient material for guided periodontal hard and soft tissue regeneration includes a 3D printed scaffold layer and an electrospun fibrous membrane layer. The content of hydroxyapatite in the 3D printed scaffold layer is higher than the content of hydroxyapatite in the electrospun fibrous membrane layer. The pore size of the 3D printed scaffold layer is larger than the pore size of the electrospun fibrous membrane layer. The pore size of the 3D printed scaffold layer is 100-1000 μm, and the fiber diameter of the electrospun fibrous membrane layer is 300-5000 nm. The electrospun fibrous membrane layer is in a random distribution or an oriented arrangement or has a mesh structure. The thickness of the electrospun fibrous membrane layer is 0.08-1 mm.

A composite implant device for use in a medical application, comprising a synthetically-derived mesh that mimics particular critical aspects of a biologically-derived mesh. The composite implant device can be used for the reinforcement and reconstruction of tissues within the body and can be comprised of a majority of synthetic components and minority of naturally-derived components which mimic the structure and function of a naturally-derived mesh.

Methods of producing composite articles and composite articles are disclosed herein. A method of producing a composite article includes providing a nonwoven fabric substrate having a surface. In some embodiments, the method may include electrospinning a nylon solution on the surface of the nonwoven fabric substrate to coat and/or impregnate the nonwoven fabric substrate with a nylon fiber.

The invention relates to a method for producing a carrier layer with a hydrophilic polymeric nanocoating wherein a polymeric carrier layer is produced with filaments of polymer material(s). Further the hydrophilic polymer nanocoating is applied by means of a low pressure plasma polymerization process using organic precursor monomers onto the polymeric carrier layer and/or composite membrane. Additionally, the invention relates to a carrier layer with a polymeric hydrophilic nanocoating.

The method to produce a packaged cosmetic product comprises a step of feeding a support film along a feed path, a step of forming a membrane substrate, and a step of packaging the membrane substrate. The method can be implemented by means of a suitable apparatus, which comprises a station for feeding the support film, a station for forming the membrane substrate, and a packaging unit, which are disposed in succession along the feed path of the support film.

The present invention provides a coating formation method with which adhesion between skin and a coating formed by electrostatic spraying is enhanced. The coating formation method of the present invention includes a liquid agent applying step of applying a liquid agent containing one or more selected from water, polyols and oils that are in a liquid form at 20° C., and an electrostatic spraying step of electrostatically spraying a composition directly on skin to form a coating. The liquid agent applying step and the electrostatic spraying step are performed in this order or in a reversed order. The composition includes a component (a) and a component (b) below: (a) one or more volatile substances selected from the group consisting of water, alcohols, and ketones, and (b) a polymer having a coating formation ability.

Provided is a method for forming a good fibrous coating on a target surface even in a high-humidity environment when electrostatically spraying is performed directly on the target surface such as skin. A composition for forming a coating of fibers on a target object by electrostatic spraying, comprising the following components (a), (b), (c) and (d): (a) 1 mass % or more and 45 mass % or less of a polymer having a film-forming ability; (b) 45 mass % to 95 mass % of one or more volatile substances selected from the group consisting of an alcohol and a ketone; (c) a conductivity controlling agent to control the conductivity of the composition to 8 μS/cm or more and 300 μS/cm or less; and (d) 0.2 mass % or more and 25 mass % or less of water.

The present invention relates to thin filters comprising melt electro spinning writing (MEW) fibers for capturing and culturing circulating tumor cells (CTCs). The invention further relates to processes for producing the filters, methods for capturing and culturing CTCs using the filters, kits and devices comprising the filters and uses of the filters.

Membranes suitable for use in membrane distillation are provided. Such membranes may include nano-fibrous layers with adjustable pore sizes. The membranes may include a hydrophobic nanofibrous scaffold and a thin hydrophilic protecting layer that can significantly reduce fouling and scaling problems.