Embodiments of the invention relate generally to electrospun fibers and, more particularly, to the controlled release of an active pharmaceutical ingredient (API) from electrospun fiber scaffolds (EFSs).

Embodiments of the invention relate generally to electrospun fibers and, more particularly, to the controlled release of an active pharmaceutical ingredient (API) from electrospun fiber scaffolds (EFSs).

The present invention discloses a method for preparing a PET/PTT parallel complex filament with high self-crimpiness, wherein PET and PTT are sliced, dried and crystallized, and then fused separately and subjected to extrusion molding through a parallel-type spinneret plate; oil is applied after cooling; then level 1-3 drafting and heat setting treatment are adopted; and during drafting, a total drafting rate is controlled to be 3 to 3.5, wherein the level-1 drafting rate is 2.8 to 3.0 at a temperature controlled to be 75 to 80? C., according to the method for preparing the PET/PTT parallel complex filament with high self-crimpiness, methods like multi-level drafting for increasing the drafting rate are adopted, and the effects of improving the fiber strength, moderately lowering the breaking elongation, and greatly improving the self-crimpiness are achieved.

Embodiments of the invention relate generally to electrospun fibers and, more particularly, to the controlled release of an active pharmaceutical ingredient (API) from electrospun fiber scaffolds (EFSs).

Embodiments of the invention relate generally to electrospun fibers and, more particularly, to the controlled release of an active pharmaceutical ingredient (API) from electrospun fiber scaffolds (EFSs).

Embodiments of the invention relate generally to electrospun fibers and, more particularly, to the controlled release of an active pharmaceutical ingredient (API) from electrospun fiber scaffolds (EFSs).