A fluid ejection device may include a first channel having a first end and a second end, a first drop ejector along the first channel, a second channel having a first end and a second end, a second drop ejector along the second channel, a third channel extending between and connecting the first end of the first channel and the first end of the second channel, a fourth channel extending between and connecting the second end of the firs channel and the second end of the second channel and a fifth channel extending between and connecting the third channel and the fourth channel.

A fluid ejection device may include a first channel having a first end and a second end, a first drop ejector along the first channel, a second channel having a first end and a second end, a second drop ejector along the second channel, a third channel extending between and connecting the first end of the first channel and the first end of the second channel, a fourth channel extending between and connecting the second end of the firs channel and the second end of the second channel and a fifth channel extending between and connecting the third channel and the fourth channel.

This disclosure provides devices and methods for the isolation of single cells or particles of interest from a solution comprising a plurality of cells or a solution composed of a homogenous population of particles. Specifically, the present disclosure is directed to microfluidic devices and methods for analyzing cells in a sample. More specifically, the present disclosure provides droplet microfluidic devices and methods for using the same to obtain (trap), encapsulate, and retrieve (isolate) single cells or particles from a sample with improved efficiency.

A thermoelectric pumping apparatus for use with a heating device includes a water receptacle. A thermoelectric device includes a “cool” side coupled to the receptacle and an opposed “hot” side, the thermoelectric device generating current upon a temperature differential between the cool and hot sides. A conduction member is proximate the hot side and in selective communication with the heating device. A spring is positioned between a top side of the conduction member and receptacle, the spring being movable between a compressed configuration at which the conduction member is in thermal communication with the hot side of the thermoelectric device and an extended configuration at which the top side of the conduction member is not in thermal communication with the hot side of the thermoelectric device. A water pump is in fluid communication with the water in the receptacle and selectively energized by the thermoelectric device to output the water.

A thermoelectric pumping apparatus for use with a heating device includes a water receptacle. A thermoelectric device includes a “cool” side coupled to the receptacle and an opposed “hot” side, the thermoelectric device generating current upon a temperature differential between the cool and hot sides. A conduction member is proximate the hot side and in selective communication with the heating device. A spring is positioned between a top side of the conduction member and receptacle, the spring being movable between a compressed configuration at which the conduction member is in thermal communication with the hot side of the thermoelectric device and an extended configuration at which the top side of the conduction member is not in thermal communication with the hot side of the thermoelectric device. A water pump is in fluid communication with the water in the receptacle and selectively energized by the thermoelectric device to output the water.

A fluid dispensing system includes a motor housing and a piston pump assembly connected to the motor housing. A motor is mounted within the motor housing. The piston pump assembly includes a pump housing, a cartridge having a first end that extends into a second end of the pump housing, a piston that extends into a first end of the pump housing and the first end of the cartridge, and a packing stack within the cartridge and adjacent an inner surface of the cartridge and through which the piston extends. The cartridge is configured to be removed from the pump housing, and removal of the cartridge removes the packing stack from within the pump housing while leaving the pump housing connected to the motor housing.

An undulatory structure and methods for the fabrication and use thereof. The undulatory structure includes a buckled sheet and one or more work input elements for deforming the buckled sheet in an undulating manner wherein each point in a series of points on a sinuously-shaped profile of the buckled sheet travels at least partially along a figure eight-shaped path. The undulatory structure can be adapted for use as a solid-state transducer wherein the buckled sheet provides mechanical advantage without appreciable opposition from elastic restoring forces, thereby achieving improved force, displacement and efficiency characteristics.

An undulatory structure and methods for the fabrication and use thereof. The undulatory structure includes a buckled sheet and one or more work input elements for deforming the buckled sheet in an undulating manner wherein each point in a series of points on a sinuously-shaped profile of the buckled sheet travels at least partially along a figure eight-shaped path. The undulatory structure can be adapted for use as a solid-state transducer wherein the buckled sheet provides mechanical advantage without appreciable opposition from elastic restoring forces, thereby achieving improved force, displacement and efficiency characteristics.

Embodiments of the present disclosure provide a device for manipulating a substance, the device comprising at least three series of interdigitated electrode pairs, wherein each electrode of each pair is connected to an electrode in an adjacent pair in the respective series by an electrical path, and a dielectric layer disposed on the at least three series of interdigitated electrode pairs, the dielectric layer comprising one or more sub layers. The at least three series of interdigitated electrode pairs are selectively and independently energisable to produce an electric field at a top surface of the dielectric layer so that a substance on the top surface may be manipulated by the electric field. The device further comprises one or more groups of the interdigitated electrode pairs, each group having a longitudinal axis, wherein in each group the respective interdigitated electrode pairs are arranged along the respective longitudinal axis such that along the respective longitudinal axis no two adjacent pairs are from a single one of the at least three series, and no pair is adjacent to two other pairs from a single one of the at least three series.

Embodiments of the present disclosure provide a device for manipulating a substance, the device comprising at least three series of interdigitated electrode pairs, wherein each electrode of each pair is connected to an electrode in an adjacent pair in the respective series by an electrical path, and a dielectric layer disposed on the at least three series of interdigitated electrode pairs, the dielectric layer comprising one or more sub layers. The at least three series of interdigitated electrode pairs are selectively and independently energisable to produce an electric field at a top surface of the dielectric layer so that a substance on the top surface may be manipulated by the electric field. The device further comprises one or more groups of the interdigitated electrode pairs, each group having a longitudinal axis, wherein in each group the respective interdigitated electrode pairs are arranged along the respective longitudinal axis such that along the respective longitudinal axis no two adjacent pairs are from a single one of the at least three series, and no pair is adjacent to two other pairs from a single one of the at least three series.