A dual latching microvalve is capable of a metastable state, wherein a one or more complete flow paths are open, before switching to another state that allows only an inlet or outlet valve to be open at any time on any fluid path. One valve mechanism uses a cam to alternately open and close two valves, with an external force applying pressure to move one valve arm onto a resting position on the cam, thereby opening the closed valve and provided an uninterrupted flow path through the dual latching microvalve. The metastable state provides, for example, a means to prime the pump before operation, such as pumping of insulin into a patient. When released from the metastable state, the dual latching microvalve operates in a fashion whereby opening of both valves simultaneously is prevented, thereby protecting the patient from injury.

The present disclosure provides an aerosol delivery device and a cartridge for an aerosol delivery device. In various implementations, the cartridge may comprise a housing defining a liquid reservoir, an atomizer configured to produce an aerosol, the atomizer comprising a first liquid transport element, a second liquid transport element, and a microvalve located between the liquid reservoir and the second liquid transport element. The microvalve may comprise a base member including at least one channel, and an actuating member at least a portion of which comprises a shape-memory material, and which is configured to move between a first position and a second position, wherein in the first position, the actuating member substantially blocks fluid flow from the liquid reservoir through the channel, and in the second position, the actuating member allows fluid flow from the liquid reservoir through the channel and to the second liquid transport element.

A valve for use in connection with microfluidic devices includes a safety feature such that flow is controlled even in the case of a loss of power, thus having applications in critical applications such as the precise delivery of drugs overtime. The valve may be used in connection with multiple tubes delivering drugs, and may be used with a pump, such as an electrochemical pump, to provide the force to move the fluids containing drugs for delivery. In certain applications, more than one medicine may be delivered and metered independently using a single pump with multiple reservoirs and valves.

A valve includes a valve housing having first and second regions, at least one valve chamber configured to be pressurized with air and including an actuating element for opening and closing a valve opening and an actuator for actuating the actuating element, both arranged in the first region. A printed circuit board extends into each valve chamber and to electrically operate the actuator, the printed circuit board(s) being connected to a common main printed circuit board arranged in the second region. Each valve chamber is surrounded by boundary surfaces closing the valve chamber in a substantially gas-tight manner. An open space open to at least two oppositely disposed sides of the valve housing extends between at least two of the valve chambers, and a connecting member of the printed circuit boards extends through connecting openings of the boundary surfaces of adjacent valve chambers and the open space. A sealing material located in the open space encloses the connecting member and the connecting openings in a gas-tight manner at least in the direction of the oppositely disposed sides. A method of manufacturing such a valve includes manufacturing a conductor element including the printed circuit boards and the main printed circuit board; introducing the conductor element into the valve housing; and filling the open space at least in part with the sealing material from at least one side after the introducing step so that the sealing material seals the connecting member and the connecting openings in a gas-tight manner at least in the direction of the oppositely disposed sides.

A dual latching microvalve is capable of a metastable state, wherein a one or more complete flow paths are open, before switching to another state that allows only an inlet or outlet valve to be open at any time on any fluid path. One valve mechanism uses a cam to alternately open and close two valves, with an external force applying pressure to move one valve arm onto a resting position on the cam, thereby opening the closed valve and provided an uninterrupted flow path through the dual latching microvalve. The metastable state provides, for example, a means to prime the pump before operation, such as pumping of insulin into a patient. When released from the metastable state, the dual latching microvalve operates in a fashion whereby opening of both valves simultaneously is prevented, thereby protecting the patient from injury.

The present disclosure provides an aerosol delivery device and a cartridge for an aerosol delivery device. In various implementations, the cartridge may comprise a housing defining a liquid reservoir, an atomizer configured to produce an aerosol, the atomizer comprising a first liquid transport element, a second liquid transport element, and a microvalve located between the liquid reservoir and the second liquid transport element. The microvalve may comprise a base member including at least one channel, and an actuating member at least a portion of which comprises a shape-memory material, and which is configured to move between a first position and a second position, wherein in the first position, the actuating member substantially blocks fluid flow from the liquid reservoir through the channel, and in the second position, the actuating member allows fluid flow from the liquid reservoir through the channel and to the second liquid transport element.

A valve includes a valve housing having first and second regions, at least one valve chamber configured to be pressurized with air and including an actuating element for opening and closing a valve opening and an actuator for actuating the actuating element, both arranged in the first region. A printed circuit board extends into each valve chamber and to electrically operate the actuator, the printed circuit board(s) being connected to a common main printed circuit board arranged in the second region. Each valve chamber is surrounded by boundary surfaces closing the valve chamber in a substantially gas-tight manner. An open space open to at least two oppositely disposed sides of the valve housing extends between at least two of the valve chambers, and a connecting member of the printed circuit boards extends through connecting openings of the boundary surfaces of adjacent valve chambers and the open space. A sealing material located in the open space encloses the connecting member and the connecting openings in a gas-tight manner at least in the direction of the oppositely disposed sides. A method of manufacturing such a valve includes manufacturing a conductor element including the printed circuit boards and the main printed circuit board; introducing the conductor element into the valve housing; and filling the open space at least in part with the sealing material from at least one side after the introducing step so that the sealing material seals the connecting member and the connecting openings in a gas-tight manner at least in the direction of the oppositely disposed sides.

A three-way (3-way) Micro-Electro-Mechanical Systems (MEMS)-based micro-valve device and method of fabrication for the implementation of a three-way MEMS-based micro-valve are disclosed. The micro-valve device has a wide range of applications, including medical, industrial control, aerospace, automotive, consumer electronics and products, as well as any application(s) requiring the use of three-way micro-valves for the control of fluids. The discloses three-way micro-valve device and method of fabrication that can be tailored to the requirements of a wide range of applications and fluid types, and can also use a number of different actuation methods, including actuation methods that have very small actuation pressures and energy densities even at higher fluidic pressures. This is enabled by a novel pressure-balancing scheme, wherein the fluid pressure balances the actuator mechanism so that only a small amount of actuation pressure (or force) is needed to switch the state of the actuator and device from open to closed, or closed to open.

This present invention utilizes a shape memory alloy (SMA) to improve on prior art in the design of clamps used for shut off, squeeze off, of plastic pipe which transmits gas or fluid under pressure. More particularly, but not exclusively, the present invention incorporates SMAs as actuators to simplify and improve clamp design for squeeze off of plastic pipe that is used in the transmission of pressurized gas and fluid. This invention may be deployed and operated remotely by the user. This present invention relates specifically to the application of trained SMA tubes, rods, bars, and beams as actuators for clamping and squeeze off of plastic pipe and tubing used to transmit gas or fluid.

A valve for switching of media, such as liquids or gases, is opened, closed or put into an intermediate state by at least one actuator produced from a shape memory alloy. The at least one actuator, as a function of whether electricity is applied to it, acts on at least one valve ball or a valve plunger accommodated in a core element, so that the through-flow of a medium through a fluid part below the core element, with a media-tight membrane interposed between, is opened, interrupted or partially opened in regulated or controlled manner. The core element is produced from a mechanically rigid and thermally well-conductive material, has electrical conductor tracks for electrical connection of the actuator to a supply of electricity on the top side, as well as multiple threaded through-holes for underside connection with the fluid part and the membrane and/or for top-side connection with the actuator.