The present disclosure is related to bioprocessing devices, systems, and methods, and particularly to sanitary connections for bioprocessing. The devices, systems, and methods described herein can relate to the sanitary connection of flow fittings, such as reducers, with considerations for ease of assembly and sealing. In some embodiments, the system may include a flow reducer, a ferrule and a gasket. The flow reducer may include a gasket channel, an overmold channel within the gasket channel, and one or more cavities within the overmold channel. The gasket may be overmolded within the gasket channel and extending within the one or more cavities.

The present disclosure is related to bioprocessing devices, systems, and methods, and particularly to sanitary connections for bioprocessing. The devices, systems, and methods described herein can relate to the sanitary connection of flow fittings, such as reducers, with considerations for ease of assembly and sealing. In some embodiments, the system may include a flow reducer, a ferrule and a gasket. The flow reducer may include a gasket channel, an overmold channel within the gasket channel, and one or more cavities within the overmold channel. The gasket may be overmolded within the gasket channel and extending within the one or more cavities.

A pipeline including at least first and second portions, each comprising outer and inner pipes, at least one coupling system connecting the first and second portions and including at least a downstream flange ring connected to at least one of the outer and inner pipes of the first portion, at least an upstream flange ring connected to at least one of the outer and inner pipes of the second portion, connecting elements connecting the upstream and downstream flange rings, first and second annular seals interposed between the upstream and downstream flange rings and configured to delimit, with the upstream and downstream flange rings, a buffer space containing an atmosphere, the pipeline comprising at least one leak detection system configured to determine at least one characteristic of the atmosphere of the buffer space.

Male or female fluid coupling element and fluid coupling including such an element This coupling element has a body and a nozzle. The body delimits a housing for partially receiving the nozzle. The nozzle has a tubular part and a flange received in the housing. Two sealing barriers formed by at least one sealing joint are interposed between a rear surface of the flange and a front face of the body, between a front surface of the flange and a rear face of the body, respectively. A plug caps an inner conduit. Portions of the inner conduit communicate through at least one passage opening into an inner volume of the nozzle, forward of the plug, and on an outer peripheral surface of the flange. An inner chamber is separated from the inner conduit by the body, the flange, the plug and the first sealing barrier.

Male or female fluid coupling element and fluid coupling including such an element This coupling element has a body and a nozzle. The body delimits a housing for partially receiving the nozzle. The nozzle has a tubular part and a flange received in the housing. Two sealing barriers formed by at least one sealing joint are interposed between a rear surface of the flange and a front face of the body, between a front surface of the flange and a rear face of the body, respectively. A plug caps an inner conduit. Portions of the inner conduit communicate through at least one passage opening into an inner volume of the nozzle, forward of the plug, and on an outer peripheral surface of the flange. An inner chamber is separated from the inner conduit by the body, the flange, the plug and the first sealing barrier.

A gasket includes a base extending circumferentially about a gasket axis, a central flange, a first arm, and a second arm. The first arm includes a first arm portion extending from the gasket base to a first radial axis and a second arm portion defining a first surface at a first angle and a second surface at a second angle, the second angle greater than the first angle. The second arm includes a third arm portion extending from the gasket base to a second radial axis that is perpendicular to the gasket axis and a fourth arm portion defining a third surface at a third angle and a fourth surface at a fourth angle, the fourth angle greater than the first angle, the fourth surface further from the third arm portion than the third surface.

A gasket 4 includes: a cylindrical body portion 10 having a communication hole 10a for providing communication between flow passage holes 2c, 2c formed in two fluid devices 2, 2, respectively; and an annular primary sealing portion 11 projecting from a radially inner side of an axially outer end portion of the body portion 10 toward an axially outer side and to be press-fitted into an annular primary sealing groove 2d formed in each fluid device 2. In a state before the primary sealing portion 11 is press-fitted into the primary sealing groove 2d, an entirety of an inner circumferential surface 10b of the body portion 10 is formed such that a diameter thereof gradually decreases from both axially outer ends thereof toward an axially inner side.

Connector assemblies, connector bodies, fluid systems including connector assemblies, and procedures for making fluid connections are disclosed.

Connector assemblies, connector bodies, fluid systems including connector assemblies, and procedures for making fluid connections are disclosed.

A pipe fitting system, including a first pipe section with at least one male end, a second pipe section with at least one female end, and a connecting means for releasably connecting the pipe sections together such that the male end is at least partially received within the female end. The connecting means comprising releasably engageable first and second connectors associated with the first and second pipe sections respectively, wherein the first connector comprises at least one outwardly extending protrusion and wherein the second connector comprises corresponding recesses adapted to releasably receive the or each protrusion of the first connector. The pipe fitting system is suitable for applications such as end of line connections, repair/replacement of fixed existing pipes, and in enabling temporary removal of pipes for maintenance or access purposes.