An apparatus for cryostorage and manipulation of a plurality of container units includes a cryochamber having a cryo-access port. The cryochamber is electrically cooled at cryogenic temperatures. A unit holder is located inside the cryochamber and is configured to hold a plurality of container units. A user access area is provided for selectively permitting access to a chosen container unit by an authenticated user who has been authenticated by the apparatus. A motive grasper is provided for selectively removing the chosen container unit from the cryochamber through the cryo-access port, and selectively placing the chosen container unit into the user access area.

An apparatus for cryostorage and manipulation of a plurality of container units includes a cryochamber having a cryo-access port. The cryochamber is electrically cooled at cryogenic temperatures. A unit holder is located inside the cryochamber and is configured to hold a plurality of container units. A user access area is provided for selectively permitting access to a chosen container unit by an authenticated user who has been authenticated by the apparatus. A motive grasper is provided for selectively removing the chosen container unit from the cryochamber through the cryo-access port, and selectively placing the chosen container unit into the user access area.

A low-temperature storage device includes an inner vessel, an outer vessel about the inner vessel, a thermal insulation layer between the inner vessel and the outer vessel, and a single heat exchanger in thermal communication with an interior of the inner vessel and adapted to be connected to at least one of an evaporator in a closed-loop refrigeration circuit and an open-loop evaporator for an externally-supplied cryogen. The inner vessel can be a vacuum-insulated vessel, and the heat exchanger can be an internal heat exchanger including at least two fluid circuits: a first circuit with one external connection and one internal connection into the inner vessel and the second circuit with two external connections.

A refrigerator includes a main body defining a first cooling space, a door configured to open and close the first cooling space of the main body, a first heat pump module disposed in the main body and configured to cool the first cooling space, an independent refrigerator that is detachably disposed in the first cooling space and defines a second cooling space separate from the first cooling space, a second heat pump module disposed in the independent refrigerator and configured to cool the second cooling space of the independent refrigerator, a main body power supply part that is disposed in the main body and configured to supply power, and an independent power supply part disposed in the independent refrigerator.

A method for freezing a liquid located in a container, in particular a liquid drug, includes exposing the container to a cooling element such as cold gas in order to freeze the liquid. The cold gas preferably flows around the container, and/or the liquid is cooled in another way in order to freeze the liquid. The container is insulated at a surface of at least one first volume portion of the container, and the container is cooled nearly immediately at a surface of a second volume portion of the container by the cold gas such that the liquid freezes through later in the at least one first volume portion than in the second volume portion.

A method for freezing a liquid located in a container, in particular a liquid drug, includes exposing the container to a cooling element such as cold gas in order to freeze the liquid. The cold gas preferably flows around the container, and/or the liquid is cooled in another way in order to freeze the liquid. The container is insulated at a surface of at least one first volume portion of the container, and the container is cooled nearly immediately at a surface of a second volume portion of the container by the cold gas such that the liquid freezes through later in the at least one first volume portion than in the second volume portion.

Provided is a refrigerator. The refrigerator includes a main body defining a storage space, a cryogenic freezing compartment provided in the storage space, and a thermoelectric module assembly disposed at one side of the cryogenic freezing compartment so that the cryogenic freezing compartment is cooled to a temperature less than that of the storage space. The cryogenic freezing compartment includes a cryogenic case into which an insulation material is filled to be thermally insulated from the storage space and in which a cryogenic freezing space is defined, a case door opening and closing the cryogenic case, and a rail assembly connecting the cryogenic case to the case door and extending and contracted in multi-stages to allow the case door to be slid to be inserted and withdrawn. The rail assembly is mounted on the cryogenic case outside the cryogenic freezing space.

An apparatus for cryostorage and manipulation of a plurality of container units includes a cryochamber having a cryo-access port. The cryochamber is electrically cooled at cryogenic temperatures. A unit holder is located inside the cryochamber and is configured to hold a plurality of container units. A user access area is provided for selectively permitting access to a chosen container unit by an authenticated user who has been authenticated by the apparatus. A motive grasper is provided for selectively removing the chosen container unit from the cryochamber through the cryo-access port, and selectively placing the chosen container unit into the user access area.

An apparatus for cryostorage and manipulation of a plurality of container units includes a cryochamber having a cryo-access port. The cryochamber is electrically cooled at cryogenic temperatures. A unit holder is located inside the cryochamber and is configured to hold a plurality of container units. A user access area is provided for selectively permitting access to a chosen container unit by an authenticated user who has been authenticated by the apparatus. A motive grasper is provided for selectively removing the chosen container unit from the cryochamber through the cryo-access port, and selectively placing the chosen container unit into the user access area.

A refrigerator includes a main body in which a first storage compartment is defined, and a heat exchange chamber defined in the main body. An evaporator received in the heat exchange chamber. A second storage compartment is provided in the first storage compartment and a quick cooling module to cool an inside of the second storage compartment is provided, where the quick cooling module heat-exchanges with a refrigerant pipe of the evaporator. The quick cooling module includes a thermal conductive unit in thermal conduction with the refrigerant pipe, and a thermoelectric device having a first surface in thermal conduction with the thermal conductive unit to heat-exchange with the thermal conductive unit when current is supplied and a second surface facing the second storage compartment.