The present invention relates to a pharmaceutical formulation for vaginal administration, wherein the formulation comprises a pharmaceutical acceptable excipient and glucono δ-lactone, wherein the glucono δ-lactone is present in an amount of 5 to 99 wt % of the formulation. The invention also relates to a pharmaceutical formulation according to the invention for use in the prevention or treatment of a urogenital fungal infection. Furthermore, the invention relates to glucono δ-lactone (formula (III)), for use in the in the prevention or treatment of a fungal infection.

Described is an oven (1) for melting precious and non-precious metals, non-metallic materials such as ashes, organic industrial waste, inorganic material such as ceramics, which are heat-resistant and not, in particular in the jewellery sector, comprising an outer unit (2) forming an inner space (6) and having an inductive thermal unit (3) positioned around the inner space (6); an inner unit (4) positioned in the inner space (6) and having a melting chamber (5) for a metal to be melted and operating in conjunction with the inductive thermal unit (3) in such a way that a heating of the inner unit (4) by the inductive thermal unit (3) causes the melting of the metal in the melting pot (5). In particular, the melting chamber (5) has an opening (11) for loading and unloading the metal. The inner unit (4) is rotatably mounted in a motor-driven fashion on the outer unit (2) about an axis of rotation (Z) suitable for mixing the metal contained in the melting chamber (5). Moreover, the outer unit (2) has rotatable supporting means (21) defining a tilting axis (Y) perpendicular to the axis of rotation (Z) and suitable for unloading liquid metal from the melting chamber (5).

One or more embodiments relates to a method of casting a creep-resistant Ni-based superalloy and a homogenization heat treatment for the alloy, The method includes forming a feed stock having Nickel (Ni) and at least one of Chromium (Cr), Cobalt (Co), Aluminum (Al), Titanium (Ti), Niobium (Nb), Iron (Fe), Carbon (C), Manganese (Mn), Molybdenum (Mo), Silicon (Si), Copper (Cu), Phosphorus (P), Sulfur (S) and Boron (B). The method further includes fabricating the creep-resistant Ni-based superalloy in a predetermined shape using the feed stock and at least one process such as vacuum induction melting (VIM), electroslag remelting (ESR) and/or vacuum arc remelting (VAR).

One or more embodiments relates to a method of casting a creep-resistant Ni-based superalloy and a homogenization heat treatment for the alloy. The method includes forming a feed stock having Nickel (Ni) and at least one of Chromium (Cr), Cobalt (Co), Aluminum (Al), Titanium (Ti), Niobium (Nb), Iron (Fe), Carbon (C), Manganese (Mn), Molybdenum (Mo), Silicon (Si), Copper (Cu), Phosphorus (P), Sulfur (S) and Boron (B). The method further includes fabricating the creep-resistant Ni-based superalloy in a predetermined shape using the feed stock and at least one process such as vacuum induction melting (VIM), electroslag remelting (ESR) and/or vacuum arc remelting (VAR).

The present invention relates to a pharmaceutical formulation for vaginal administration, wherein the formulation comprises a pharmaceutical acceptable excipient and glucono δ-lactone, wherein the glucono δ-lactone is present in an amount of 5 to 99 wt % of the formulation. The invention also relates to a pharmaceutical formulation according to the invention for use in the prevention or treatment of a urogenital fungal infection. Furthermore, the invention relates to glucono δ-lactone (formula (III)), for use in the in the prevention or treatment of a fungal infection.

The present invention relates to a pharmaceutical formulation for vaginal administration, wherein the formulation comprises a pharmaceutical acceptable excipient and glucono δ-lactone, wherein the glucono δ-lactone is present in an amount of 5 to 99 wt % of the formulation. The invention also relates to a pharmaceutical formulation according to the invention for use in the prevention or treatment of a urogenital fungal infection. Furthermore, the invention relates to glucono δ-lactone (formula (III)), for use in the in the prevention or treatment of a fungal infection.

The functional condition of an induction crucible furnace is checked by first establishing a set-point parameter corresponding to an optimum functional condition of the induction crucible furnace and characterizing the vibratory behavior of same. Then, during normal operation of the furnace, an actual-value parameter of the vibratory behavior is determined. These two parameters are then compared and, if a magnitude of a difference therebetween exceeds a threshold, an alarm is generated.

A process for directional solidification of a cast part comprises energizing a primary inductive coil coupled to a chamber having a mold containing a material; generating an electromagnetic field with the primary inductive coil within the chamber, wherein said electromagnetic field is partially attenuated by a susceptor coupled to said chamber between said primary inductive coil and said mold; determining a magnetic flux profile of the electromagnetic field after it passes through the susceptor; sensing a component of the magnetic flux in the interior of the susceptor proximate the mold; positioning a mobile secondary compensation coil within the chamber; generating a control field from a secondary compensation coil, wherein said control field controls said magnetic flux; and casting the material within the mold.

Described is an oven (1) for melting precious and non-precious metals, non-metallic materials such as ashes, organic industrial waste, inorganic material such as ceramics, which are heat-resistant and not, in particular in the jewellery sector, comprising an outer unit (2) forming an inner space (6) and having an inductive thermal unit (3) positioned around the inner space (6); an inner unit (4) positioned in the inner space (6) and having a melting chamber (5) for a metal to be melted and operating in conjunction with the inductive thermal unit (3) in such a way that a heating of the inner unit (4) by the inductive thermal unit (3) causes the melting of the metal in the melting pot (5). In particular, the melting chamber (5) has an opening (11) for loading and unloading the metal. The inner unit (4) is rotatably mounted in a motor-driven fashion on the outer unit (2) about an axis of rotation (Z) suitable for mixing the metal contained in the melting chamber (5). Moreover, the outer unit (2) has rotatable supporting means (21) defining a tilting axis (Y) perpendicular to the axis of rotation (Z) and suitable for unloading liquid metal from the melting chamber (5).

A process for directional solidification of a cast part comprises energizing a primary inductive coil coupled to a chamber having a mold containing a material; generating an electromagnetic field with the primary inductive coil within the chamber, wherein said electromagnetic field is partially attenuated by a susceptor coupled to said chamber between said primary inductive coil and said mold; determining a magnetic flux profile of the electromagnetic field after it passes through the susceptor; sensing a component of the magnetic flux in the interior of the susceptor proximate the mold; positioning a mobile secondary compensation coil within the chamber; generating a control field from a secondary compensation coil, wherein said control field controls said magnetic flux; and casting the material within the mold.