Disclosed herein are systems, methods, and devices for calibrating contrast measurements from laser speckle imaging systems to accurately determine unknown particle motion characteristics, such as flow rate. The calibration stores to memory calibration data, which may include a set of measurements from samples with known particle characteristics and/or estimates of noise, including the effects on contrast arising from undesired signals unrelated to the unknown particle motion characteristics. The calibration data may be accessed and used to correct an empirical measurement of contrast and/or interpolate a value of the unknown particle motion characteristic. The system may include a light source, photodetector, processor, and memory, which can be combined into a single device, such as a wearable device, for providing calibrated flow measurements. The device may be used, for example, to measure blood flow, cardiac output, and heart rate, and can be used to amplify the pulsatile signal.

Disclosed herein are systems, methods, and devices for calibrating contrast measurements from laser speckle imaging systems to accurately determine unknown particle motion characteristics, such as flow rate. The calibration stores to memory calibration data, which may include a set of measurements from samples with known particle characteristics and/or estimates of noise, including the effects on contrast arising from undesired signals unrelated to the unknown particle motion characteristics. The calibration data may be accessed and used to correct an empirical measurement of contrast and/or interpolate a value of the unknown particle motion characteristic. The system may include a light source, photodetector, processor, and memory, which can be combined into a single device, such as a wearable device, for providing calibrated flow measurements. The device may be used, for example, to measure blood flow, cardiac output, and heart rate, and can be used to amplify the pulsatile signal.

Devices, systems, and methods are disclosed for improved laser speckle imaging of samples, such as vascularized tissue, for the determination of the rate of movement of light scattering particles within the sample. The system includes a structure adjoining a light source and a photo-sensitive detector. The structure can be positioned adjacent the sample (e.g., coupled to the sample) and configured to orient the light source and detector relative the sample such that surface reflections, including specular reflections and diffuse reflections, are discouraged from entering the detection field of the detector. The separation distance along the structure between the light source and the detector may further enable selective depth penetration into the sample and biased sampling of multiply scattered photons. The system includes an operably coupled processor programmed to derive contrast metrics from the detector and to relate the contrast metrics to a rate of movement of the light scattering particles.

A method for operating a thermal flow sensor includes: bringing a measuring medium into thermal contact with a sensor element of the flow sensor and periodically heating the medium using an AC voltage introduced into the sensor element; simultaneously detecting a maximum amplitude of a temperature and/or a phase shift between a curve of the AC voltage and the curve of the temperature; adjusting the detected maximum amplitude and/or the detected phase shift using calibration data; determining an isoline using the adjusted maximum amplitude and/or the adjusted phase shift based on model of the flow sensor, wherein the isoline has a plurality of value pairs of thermal conductivity and thermal capacitance of the medium; deriving a medium information from the isoline; and performing a flow measurement by converting signal values from the sensor element into measurement values of an effective flow velocity of the medium using the medium information.

A method determines a measured quantity relating to the flow of a fluid through a measuring tube, in two propagation directions, and a receive signal is captured. A transit time difference is determined depending on the position of the main maximum of a cross-correlation of the receive signals. Whereupon the measured quantity is determined depending on the transit time difference, and the transmitting ultrasonic transducer is controlled in each case with an excitation signal. The excitation signal has a fixed carrier frequency. The excitation signal has a phase shift and/or an envelope with a plurality of temporally spaced maxima, and/or, if a trigger condition is fulfilled, the fulfilment of which depends on the height of the main maximum and/or of at least one secondary maximum of the cross-correlation. The determination of the measured quantity is modified compared with a normal operating mode and/or a message is output.

A method determines a measured quantity relating to the flow of a fluid through a measuring tube, in two propagation directions, and a receive signal is captured. A transit time difference is determined depending on the position of the main maximum of a cross-correlation of the receive signals. Whereupon the measured quantity is determined depending on the transit time difference, and the transmitting ultrasonic transducer is controlled in each case with an excitation signal. The excitation signal has a fixed carrier frequency. The excitation signal has a phase shift and/or an envelope with a plurality of temporally spaced maxima, and/or, if a trigger condition is fulfilled, the fulfilment of which depends on the height of the main maximum and/or of at least one secondary maximum of the cross-correlation. The determination of the measured quantity is modified compared with a normal operating mode and/or a message is output.

Systems and methods are provided for estimating the flow velocity of a multi-phase flow in a pipe using injected microbubbles in combination with ultrasonic signals produced by transducers external to the pipe. The transducers can be located so that one transducer/receiver pair is downstream from a second pair by a separation distance. The receivers can preferably be located in alignment with the transducers for receiving a desirable amount of signal emitted from microbubbles that are excited by absorption of energy from a signal generated by a transducer. The frequency of the signal emitted by the microbubbles can correspond to a harmonic and/or sub-harmonic of the frequency of the signal generated by the transducer. In order to improve the signal-to-noise ratio, frequencies corresponding to a primary frequency emitted by a transducer can be filtered out.

Systems and methods are provided for estimating the flow velocity of a multi-phase flow in a pipe using injected microbubbles in combination with ultrasonic signals produced by transducers external to the pipe. The transducers can be located so that one transducer/receiver pair is downstream from a second pair by a separation distance. The receivers can preferably be located in alignment with the transducers for receiving a desirable amount of signal emitted from microbubbles that are excited by absorption of energy from a signal generated by a transducer. The frequency of the signal emitted by the microbubbles can correspond to a harmonic and/or sub-harmonic of the frequency of the signal generated by the transducer. In order to improve the signal-to-noise ratio, frequencies corresponding to a primary frequency emitted by a transducer can be filtered out.

A system is disclosed for measuring fluid flow. The system may include a plurality of sensors and a computing device. The plurality of sensors may be positionable at different angles in a container of an offshore drilling rig to sense data about drilling fluid flow in the container. The computing device may be communicatively couplable to the plurality of sensors for receiving the data about the drilling fluid flow in the container and using the data to determine a calculated fluid flow rate compensating for movement of the offshore drilling rig.

Provided herein are improved methods for estimating the flow velocity of a fluid in a vessel. Systems and methods are provided herein related to making and/or refining velocity measurements for flowing fluids, both single and multi-phase fluids, in vessels, such as pipes or conduits, utilizing contrast media property agent variations. In one aspect, this disclosure provides a method of determining a flow velocity of a fluid flow in a vessel including: providing a fluid flow having contrast media, the contrast media having a contrast media property variation; providing a detectable signal corresponding to the contrast media property variation; collecting the detectable signal at an upstream receiver to produce a first received signal; collecting the detectable signal at a downstream receiver to produce a second received signal, the downstream receiver being located downstream of the upstream receiver at a distance (L); filtering the first received signal and the second received signal through a contrast media variant filter to produce a first filtered signal and a second filtered signal; cross-correlating the first filtered signal and the second filtered signal to determine a time shift (Δt) between the first filtered signal and the second filtered signal; and estimating the velocity of the fluid flow using this relationship vflow=L/Δt.