A handheld solids dispenser. The dispenser includes a housing defining an inlet passage and an outlet passage. A delivery mechanism is supported within the housing and is positioned between the inlet passage and the outlet passage. Actuation of the delivery mechanism causes the delivery mechanism to transport a desired amount of solids material from the inlet passage to the outlet passage. The delivery member may be in the form of a plunger slidably positioned within the housing. The delivery mechanism may be in the form of a screw conveyor driven by a drive motor.

The present invention provides for a method for the treatment of a respiratory disease, disorder or condition, or a viral infection or viral disease, disorder or condition in a subject, the method comprising the step of administering to said subject a medically active liquid in nebulized form by inhalation, wherein the medically active liquid comprises niclosamide or a pharmaceutically acceptable salt thereof and wherein the medically active liquid is administered in nebulized form using an inhalation device.

Embodiments described herein generally relate to devices, systems and methods for measuring a volume or number of doses remaining in a drug delivery device that is used for delivering a dose to a patient. In some embodiments, a dose measurement system for measuring the liquid volume in a container includes a light guide disposed and configured to reflect electromagnetic radiation toward the container. The dose measurement system also includes a light guide disposed and configured to emit electromagnetic radiation into the light guide. A plurality of sensors are located in the apparatus that are optically coupleable to the light guide and are disposed and configured to detect the electromagnetic radiation emitted by at least a portion of the light guide. The apparatus also includes a processing unit configured to receive data representing the portion of the detected electromagnetic radiation from each of the plurality of sensors. The processing unit is further operable to convert the received data into a signature representative of the electromagnetic radiation detected by the plurality of sensors.

A Substance Dispenser and a Method of Providing a Substance Dispenser The invention provides a substance dispenser for dispensing a metered amount of a substance such as a cream or gel, other viscous or non-viscous substance, the dispenser comprising: a first housing member defining a handle for the dispenser; a cream containing chamber arranged to slide telescopically with respect to the handle member, the cream containing chamber having a nozzle opening at a first end, from which cream is, in use, dispensed; a bearing at the second axial end; and a shaft rotatably fixed with respect to the handle and arranged to pass through the bearing such that upon rotation of the handle with respect to the cream containing chamber, the cream containing chamber and the handle move telescopically with respect to each other such that, the substance containing chamber moves axially within the handle to force cream through the nozzle opening, wherein movement of the handle with respect to the cream containing chamber is indexed so as to dispense a predetermined volume of cream in dependence on a rotation thereof.

Provided is a system and method for a vaporizer cartridge system wherein the cartridge provides the diffuser. More specifically, an embodiment of the system includes a vaporizing device providing a heating element proximate to a removable cartridge system receiving port, and a dispenser trigger structured and arranged to engage the removable cartridge to dispense a predetermined amount of a liquid concentrate from within the removable cartridge. The system further includes a cartridge with diffuser including: a housing; a reservoir of liquid concentrate; a diffuser element; a metered dispenser structured and arranged to dispense from the reservoir into the diffuser element a predetermined amount of liquid concentrate. An associated method of use is also provided.

The present invention provides for a method for the treatment of a respiratory disease, disorder or condition, or a viral infection or viral disease, disorder or condition in a subject, the method comprising the step of administering to the subject a medically active liquid in nebulized form by inhalation, wherein the medically active liquid comprises niclosamide or a pharmaceutically acceptable salt thereof and wherein the medically active liquid is administered in nebulized form using an inhalation device, and wherein the inhalation device used to administer the medically active liquid comprising the niclosamide or a pharmaceutically acceptable salt thereof is a soft-mist-inhaler.

A dispenser includes a dispenser body and a base, wherein the base is attached to the dispenser body and a piston in the base is seated in a fluid passage of the dispenser body to define a dispensing chamber which may be filled by movement of the dispenser body relative to the base and emptied by the return of the dispenser body to the original position relative to the base.

An initial positioning system and method for liquid measuring and taking. The system comprises a measuring passage, a variable pressure chamber, and a piston, an initial end of the measuring passage being in communication with the upper part of the variable pressure chamber; the piston reciprocates in the variable pressure chamber to cause a change between positive pressure and negative pressure in the variable pressure chamber; the initial positioning system further comprises a pressure relief port located on the wall of the variable pressure chamber and capable of communicating with the outside of the variable pressure chamber; when the piston is located at the pressure relief port, and the inside and outside of the variable pressure chamber are in communication, the maximum volume of the liquid that can be accommodated in the variable pressure chamber is not smaller than one third of the total volume of the variable pressure chamber.

An arrangement for activating an aerosol dispenser having a conveying tube for conveying a liquid; a movable holding member holding the conveying tube; a rotatable base; and a container chamber between the holding member and the base, wherein the arrangement is configured to transmit a loading rotation of the base to a substantially axial loading movement of the holding member towards the base, and wherein the holding member has a locking structure exposed to the container chamber. An aerosol dispenser having the arrangement and a method for activating an aerosol dispenser are also provided.

A tensioning arrangement for an aerosol dispenser is presented where the tensioning arrangement has a conveying tube; an elastic member arranged to store mechanical energy from a substantially axial tensioning movement of the conveying tube; a rotatable member; a transmission mechanism configured to transmit a tensioning rotation of the rotatable member to the tensioning movement of the conveying tube, wherein the transmission mechanism has a cam profile and a cam follower arranged to follow the cam profile, wherein the cam profile has at least one priming structure; and wherein the tensioning arrangement is configured such that the conveying tube makes a temporary priming movement towards an initial position when the cam follower passes each priming structure during the tensioning movement of the conveying tube by means of the tensioning rotation of the rotatable member. An aerosol dispenser is also provided.