An apparatus for individually storing multiple tissue samples separately from each other includes a base, a lid, a lock, and one or more vents. The base defines a plurality of reservoirs and a plurality of identification areas. A portion of the base defines an opening corresponding to each reservoir. The lid is configured to secure the multiple tissue samples within a corresponding reservoir by enclosing each corresponding opening in the closed configuration. The lock is configured to selectively lock the lid against the base in the closed configuration. The one or more vents are configured to enable entry of fluid into the reservoirs when the lid is in the closed configuration. The one or more vents are further configured to prevent exit of tissue samples from the reservoirs when the lid is in the closed configuration.

A microtomy system includes a tissue chuck configured to accept a tissue block and a microtome blade configured to remove one or more tissue sections from the tissue block, the microtome blade being axially offset from the tissue chuck along a horizontal axis, where the microtome blade and the tissue chuck are axially displaceable relative to one another along the horizontal axis. The system also includes a control system configured to receive information indicative of a relative axial location of the microtome blade to the tissue chuck along the horizontal axis, and to use a control loop to control the relative axial location of the microtome blade to the tissue chuck such that the one or more tissue sections have a desired thickness.

The present invention addresses the problem of a tissue piece treating apparatus in which drying in an inside of a treating tank is promoted, compared with conventional tissue piece treating apparatuses, and the gas in the inside of the treating tank is discharged so that a risk of inflammation can be prevented. As a solution, a tissue piece treating apparatus (10) according to the present invention includes: a treating tank (18) in which a tissue piece is housed, and immersion of the tissue piece is performed by a chemical solution being supplied thereto; a communication passage (34) that is connected to the treating tank (18); one or a plurality of chemical solution bottles (24) that are connected to the treating tank (18) through the communication passage (34), and store chemical solutions to be supplied to the treating tank (18); and a pump (60) that causes an inside of the treating tank (18)to be a negative pressure to supply the chemical solution from the chemical solution bottle (24) to the inside of the treating tank (18), and causes the inside of the treating tank (18) to be a positive pressure to discharge the chemical solution from the inside of the treating tank (18) to the chemical solution bottle (24), in which the communication passage (34), which partially branches, includes an outside air port (42) that communicates with an outside air, and is thus configured to be able to supply and discharge the outside air to and from the inside of the treating tank (18) by receiving an action of the pump (60).

A tissue processing station includes a housing and a first heated plate that is either disposed on or forms a first horizontally oriented surface of the housing. The first heated plate is configured to either (i) contain water, or (ii) receive a dish containing water. The tissue processing station may also include a vertically-oriented heated well for heating slides. A second heated plate is either disposed on or forms an angled surface of the housing for supporting one or more laboratory slides. The angled surface is angled relative to the first horizontally oriented surface. A third heated plate is either disposed on or forms a second horizontally oriented surface of the housing for supporting one or more laboratory slides. The first and second horizontally oriented surfaces are defined at different elevations on the housing. The angled surface extends between the two horizontally oriented surfaces.

There is provided an automated system for preparing tissue samples that comprises one or more microtomes, a hydration system, and a processor, the processor being programmed to initiate facing, by one or more microtomes, of a first tissue block comprising a first tissue sample embedded in an embedding material, and cause the first tissue block to be hydrated by the hydration system for a first predetermined time, and initiate facing, by one or more microtomes, of a second tissue block while the first tissue block is being hydrated, the second tissue block comprising a second tissue sample embedded in an embedding material, and cause the second tissue block to be hydrated by the hydration system for a second predetermined time, and to initiate the one or more microtomes to begin sectioning of the first tissue block while the second tissue block is being hydrated.

A tissue processing station includes a housing and a first heated plate that is either disposed on or forms a first horizontally oriented surface of the housing. The first heated plate is configured to either (i) contain water, or (ii) receive a dish containing water. The tissue processing station may also include a vertically-oriented heated well for heating slides. A second heated plate is either disposed on or forms an angled surface of the housing for supporting one or more laboratory slides. The angled surface is angled relative to the first horizontally oriented surface. A third heated plate is either disposed on or forms a second horizontally oriented surface of the housing for supporting one or more laboratory slides. The first and second horizontally oriented surfaces are defined at different elevations on the housing. The angled surface extends between the two horizontally oriented surfaces.

A processor assembly including a core module operable to expose a sample on a slide; a staining module operable to apply a stain to the exposed sample; and a robotic transfer mechanism to transfer the slide from the core module to the staining module. Also, an apparatus including a rectangular body having an open rear end and an opposite front end; a flange having a first side and a second side, wherein the first side of the flange is coupled to the front end of the body; and a pair of legs extending from second side of the flange, wherein the pair of legs are operable to engage opposite side edges of a slide. A method comprising: exposing a sample on a slide in a core module of a processor assembly; robotically transferring the slide from the core module of the processor assembly to a staining module of the processor assembly; applying a reagent to the exposed sample in the staining module by a thermal inkjet printing process; and after applying the reagent, robotically transferring the slide back to the core module.

A system for monitoring tissue samples to be processed by a tissue processor for a histopathology workflow, the system including: a scanner associated with the tissue processor arranged to scan an electronic sample identifier of at least one tissue sample to be processed by the tissue processor; an input module arranged to receive tissue processor workflow data indicative of a tissue processor workflow for the at least one tissue sample to be processed by selected ones of a plurality of processing stations in the tissue processor used for processing the at least one tissue sample; a monitoring module arranged to monitor properties of the at least one tissue sample processed at each of the selected ones of the processing stations and to record the properties of the at least one tissue sample in association with the electronic sample identifier in a sample record for the tissue processor workflow; and an output module arranged to output the sample record to one or more laboratory instruments for further processing the at least one tissue sample in a histopathology workflow. A tissue processor for processing tissue samples for a histopathology workflow is also provided. A method of monitoring tissue samples to be processed by a tissue processor for a histopathology workflow is also provided.

There is provided a histology system that comprises a microtome configured to expose a face of a tissue block comprising a tissue sample embedded in an embedding material and remove one or more tissue sections from the sample, a hydration system configured to hydrate the tissue block by depositing a hydrating liquid on the face of the tissue block, and a transfer system configured to transfer the one or more tissue sections from the microtome to one or more slides. In some embodiments, the hydration system is configured to produce droplet condensation of the hydrating liquid and deposit the condensation on the face of the tissue block.

A method of operating a tissue processor for processing tissue samples is provided. The tissue processor includes at least one retort for receiving tissue samples, at least one container for storing a reagent, and at least one sensor arranged for fluid communication with one or both of the at least one container and the at least one retort for measuring a measured purity level of a reagent. The method includes the steps of conducting reagent from the at least one container or the at least one retort to the at least one sensor, automatically measuring, by means of the at least one sensor, a measured purity level of the reagent, checking whether the measured purity level meets a predetermined purity level of the reagent associated with the at least one container, and automatically determining, based on a result of checking, whether the reagent is suitable for processing tissue samples in the tissue processor. A tissue processor for processing tissue samples is also provided. A container is also provided for storing tissue samples for processing in a tissue processor.