A tube for mixing, diluting and preserving a sample includes a hollow first container for receiving and storing a solution, the first container having first and second ends, wherein at least the first end has a through-hole, and a transport-pin located in the through-hole of the first end having a shape closely matching to the through-hole, the transport-pin including a recess with a predetermined size. The recess is suitable to be filled by a sample, wherein the transport-pin is movable between an initial position in which the recess is positioned at least partially on the outer side of the first container, and an end position in which the recess is positioned at least partially on the inner side of the first container.

Mercury vapor reference systems, devices, and method for testing mercury vapor analyzers. A variable volume dilution chamber such as a syringe selectively receives mercury vapor and a dilution gas to dilute the mercury vapor prior to dispensing into an airflow for testing by the mercury vapor analyzer.

Devices and methods for biological sample preparation are provided herein. Components of such devices include a plurality of plungers that can be actuated for metering and/or mixing one or more agents. Methods of manufacturing such devices using 3D printing are also provided.

This disclosure relates to apparatus and methods for molecular diagnostics. Certain embodiments include a piston cycled from a first position proximal to a first end of a housing, to a second position proximal to a second end of the housing, and back to the first position proximal to the first end of the housing. In some embodiments, the present disclosure relates to devices, methods, and systems for molecular diagnostics that do not comprise a piston.

A fluid transfer device comprising a first reservoir (1) having a predetermined sub-ambient pressure and volume and a presealed opening (1a), a second reservoir (2) containing a predetermined volume of a fluid (M) and having a presealed opening (2a), and a chamber (3) having an internal space (6) and an inlet (4) to the space (6) adapted to be connected to the opening (2a) of the second reservoir (2) and an outlet (5) from the space (6) adapted to be connected to the opening (1a) of the first reservoir (1).

A tube for extracting, diluting and discharging a sample: able to control the amount of discharged diluted solution in the tube, after the sample has been diluted; that improves the hygienic conditions of discharging the sample; that enables introduction of a predetermined amount of a sample in any liquid or solid state; and that is able to transfer a specific amount of a diluted sample into another tube for further processing without any hygienic problems and with no risk of accidents.

A method for diluting a sample includes drawing an aliquot of the sample past a mixing junction. The method also includes supplying the sample to the mixing junction and supplying a second fluid to the mixing junction. The second fluid mixes with the sample at the mixing junction to generate a diluted sample. The method further includes supplying the diluted sample from the mixing junction.

A fluid transfer device comprising a first reservoir (1) having a predetermined sub-ambient pressure and volume and a presealed opening (1a), a second reservoir (2) containing a predetermined volume of a fluid (M) and having a presealed opening (2a), and a chamber (3) having an internal space (6) and an inlet (4) to the space (6) adapted to be connected to the opening (2a) of the second reservoir (2) and an outlet (5) from the space (6) adapted to be connected to the opening (1a) of the first reservoir (1).

A device for shaking samples includes a carrier (62), a drive element (66) which is rotatably bearing-mounted on the carrier (62), and a tray (61) arranged for loading with the samples (69). Furthermore, the device includes a tray shaft (67), which is connected to the tray (61) and is bearing-mounted eccentrically on the drive element (66), and an openable housing (64). The tray (61), the tray shaft (67), the drive element (66) and the carrier (62) are located in an interior space within the housing (64). In addition, the device includes a main drive shaft (63) drivable by a drive (65) and which extends orthogonally to the tray (61) at least partially through the housing (64). The drive element (66) is drivable via the main drive shaft (63). The carrier (62) together with the tray (61) is pivotably bearing-mounted about the main drive shaft (63), wherein the carrier (62) together with the tray (61) is at least partially pivotable out of the housing (64) in the open state.

A multi-stage fluid conditioning device formed to receive a series of drop-in modular conditioning components, the exemplary embodiment in the form of single-stage regulators, is provided for stepped pressure reduction in radial and stacked configurations, the system providing enhanced efficiencies including reduced footprint as well as easy access to individual stages for repair, maintenance or reconfiguration, even in the field, via the provision of an exterior access port for each conditioning component in the device in alternative configurations, the present device further providing enhanced energy efficiencies, decreased cost of implementation, and significantly reduced complexity, when compared to prior systems.