The present invention includes: a cell holding body that holds a measurement cell housing a measurement sample and a dispersion medium; a cover attached to the cell holding body so as to cover the measurement cell; a rotation section that rotates the cell holding body and applies centrifugal force to the measurement cell; a light source that is provided on one side of a rotation passage region of the measurement cell and irradiates the cell with light; a photodetector that is provided on another side of the rotation passage region of the measurement cell and detects light transmitted through the cell; and a particle diameter distribution arithmetic section that acquires a light intensity signal from the photodetector and calculates a particle diameter distribution. The rotation passage region of the cover is located inside an optical path of light passing between the light source and the photodetector.

A method for processing particles contained in a liquid biological sample is presented. The method uses a rotatable vessel for processing particles contained in a liquid biological sample. The rotatable vessel has a longitudinal axis about which the vessel is rotatable, an upper portion comprising a top opening for receiving the liquid comprising the particles, a lower portion for holding the liquid while the rotatable vessel is resting, the lower portion comprising a bottom, and an intermediate portion located between the upper portion and the lower portion, the intermediate portion comprising a lateral collection chamber for holding the liquid while the rotatable vessel is rotating. The method employs dedicated acceleration and deceleration profiles for sedimentation and re-suspension of the particles of interest.

An apparatus for determining a vertical position of at least one interface between a first component and at least one second component, the components comprised as different layers in a sample container. The apparatus comprises a first sensing unit and a first light detector configured to generate a first sensing signal, a second sensing unit comprising a second light detector configured to generate a second sensing signal, a driving unit configured to move the sample container, a position sensing unit configured to output a position sensing signal indicative of a vertical position of the sample container, a vertical position determining unit configured to match the first and the second sensing signal such that first and the second sensing signal correspond to identical vertical positions, and to determine the vertical position of the at least one interface in response to the matched sensing signals and the position sensing signal.

An object of the present claimed invention is to improve cell cooling performance, keep a temperature of a dispersion medium constant, and improve measurement accuracy. The particle size distribution measuring device of this invention comprises a cell holding body 31 that holds a cell 2 housing a measurement sample and that is rotated by a motor 322, a case (C) having a housing space (S) for rotatably housing the cell holding body 31, and a cooling mechanism 8 for cooling the cell 2. The cooling mechanism 8 comprises a cooler 81, and a supply channel 82 that supplies a gas that has been cooled by the cooler 81 to the housing space (S).

An apparatus includes a collection tube for containing a sample, a reading cell container including windows, the collection tube linked to the reading cell container to provide the sample to the reading cell container, a collimated light source composed in such way that light passes through the windows of the reading cell container and is reflected therein, an optical detector for the evaluation of collimated light attenuated by the sample within the reading cell container; and an electronic control device linked to the collection tube, collimated light source and optical detector.

The disclosure describes methods and devices with which to process and analyze difficult chemical, biological, environmental samples including but not limited to those containing bulk solids or particulates. The disclosure includes a cartridge which contains a separation tube as well as one or more valves and cavities for receiving raw sample materials and for directing and containing various fluids or samples. The cartridge may contain a separation fluid or density medium of defined density, and structures which direct particulates toward defined regions of the cartridge. Embodiments can include a rotational device for rotating the cartridge at defined rotational rates for defined time intervals. Embodiments allowing multiple assays from a single sample are also disclosed. In some embodiments, this device is used for direct processing and chemical analysis of food, soil, blood, stool, motor oil, semen, and other samples of interest.

A device for detecting particles in a lubricating oil of a machine, comprising a particle separator; at least one particle detector; a bypass conduit for the particle-concentrating oil, fluidly connected to an oil outlet of the particle separator, concentrating the particles; and wherein the at least one particle detector is operatively mounted on the bypass conduit so as to be able to detect particles in the bypass conduit.

To improve the measurement accuracy of a particle size distribution measuring device that performs a particle size distribution measurement in a line start mode. A measurement cell used in a line start mode of a centrifugal sedimentation type particle size distribution measuring device includes: a cell main body that has an opening provided on one end and stores therein a density gradient liquid W.sub.DGS; and a cell cap that closes the opening of the cell main body and has an internal passage R provided therein for holding a sample liquid W.sub.SS. When an application of a centrifugal force is received, the sample liquid W.sub.SS is introduced from the internal passage R into the density gradient liquid W.sub.DGS.

A method for automated identification of a state of a sample such as, for example, for identifying whether or not the sample was centrifuged is presented. A device for analyzing samples and a laboratory automation system are also presented in which the method is applied.

Analytical assay reaction cartridges, kits containing same, and methods of production and use thereof are disclosed. These cartridges include a magnetic assembly that surrounds at least a portion of a sample read window on the cartridge. The cartridge also includes an analytical reagent positioned therewithin, wherein the analytical reagent comprises magnetic beads coated with at least one anti-red blood cell antibody.