G01N2021/0325

Portable Cannabidiol Testing Device

A Portable cannabidiol testing system which operates by selectively using specific visible wavelengths of light which are absorbed by the cannabidiol (CBD) chemical compound. The visible light spectrum source is tuned to wavelengths of light absorbed by the cannabidiol chemical compound. The testing system allows for verification of CBD content within a sample. The system utilizes a single use container with a premeasured reagent which allows for a reduction in the number of steps required for the testing process. An intrinsically safe light source and sensor are tuned to at least one specific wavelength of CBD light absorption and submerged in the CBD/Acetone reagent solution.

Target Analysis Chip and Target Analysis Method

The present invention provides a novel target analysis chip and analysis method for directly detecting a target such as a microRNA without performing PCR.

MICROFLUIDIC REACTION CHAMBER WITH A REACTION CHAMBER CIRCUIT

A microfluidic reaction chamber with a reaction chamber circuit includes a microfluidic reaction chamber to contain a reaction fluid for amplification of nucleic acids, and a reaction chamber circuit disposed within the microfluidic reaction chamber. The microfluidic reaction chamber includes a base wall, a top wall parallel to the base wall and defined in part by a transparent lid, a first side wall, and a second side wall. The reaction chamber circuit is disposed within the microfluidic reaction chamber, and includes a top surface, a bottom surface, a first side wall, and a second side wall. The reaction chamber circuit is in fluidic contact with the reaction fluid and includes a photodetector to detect a fluorescence signal from a labeled fluorescent tag in the reaction fluid.

Integrated optoelectronic read head and fluidic cartridge useful for nucleic acid sequencing

A detection apparatus having a read head including a plurality of microfluorometers positioned to simultaneously acquire a plurality of the wide-field images in a common plane; and (b) a translation stage configured to move the read head along a substrate that is in the common plane. The substrate can be a flow cell that is included in a cartridge, the cartridge also including a housing for (i) a sample reservoir; (ii) a fluidic line between the sample reservoir and the flow cell; (iii) several reagent reservoirs in fluid communication with the flow cell, (iv) at least one valve configured to mediate fluid communication between the reservoirs and the flow cell; and (v) at least one pressure source configured to move liquids from the reservoirs to the flow cell. The detection apparatus and cartridge can be used together or independent of each other.

Optical system, and method of illuminating a sample plane

Various embodiments may provide a method of illuminating a sample plane. The method may include providing an illumination subsystem, the illumination subsystem including an optical source and at least one lens, having an optic axis at an incident angle greater than 0° and less than 90° to a normal of the sample plane. The method may also include rotating the illumination subsystem about a pivot point between the optical source and the sample plane along the optic axis so that an adjusted illumination distribution generated by the illumination subsystem at the sample plane has greater symmetry compared to a reference illumination distribution generated by the illumination subsystem at the sample plane without the rotation about the pivot point.

METHOD AND APPARATUS FOR MEASURING PHYSIOLOGICAL PROPERTIES OF BIOLOGICAL SAMPLES
20230228743 · 2023-07-20 ·

The present disclosure relates to methods and apparatus for measuring of multiple physiological properties of biological samples, such as measuring biological flux.

Optical detection for bio-entities

An integrated semiconductor device for manipulating and processing bio-entity samples and methods are described. The device includes a lower substrate, at least one optical signal conduit disposed on the lower substrate, at least one cap bonding pad disposed on the lower substrate, a cap configured to form a capped area, and disposed on the at least one cap bonding pad, a fluidic channel, wherein a first side of the fluidic channel is formed on the lower substrate and a second side of the fluidic channel is formed on the cap, a photosensor array coupled to sensor control circuitry, and logic circuitry coupled to the fluidic control circuitry, and the sensor control circuitry.

Biological material, measuring instrument
11536635 · 2022-12-27 · ·

A biological material measuring instrument is described. The biological material measuring instrument includes a rotating body and a main body. The rotating body includes one or more cartridge holders having cuvettes in which a reagent and an analyte in a sample react. The main body includes a pair of light-emitting parts and light-receiving parts to optically measure the analyte in the sample. The rotating body further includes a light-emitting optical waveguide for guiding the light of the light-emitting parts to the cuvette and a light-receiving optical waveguide for guiding.

Device and Method for Determination of a Catalyst State in a Chemical Reactor
20220373524 · 2022-11-24 ·

The invention pertains to a device for determination of a catalyst state in a chemical reactor and to a method for detecting a catalyst state under in situ reaction conditions. A reactor is provided with a solid catalyst provided in a reactor chamber. A fluid sample is taken from the reactor chamber and is transferred to a sample chamber. The temperature at the extraction site of the sample in the reactor chamber is determined and the temperature of the sample chamber is adjusted to the same temperature. A small amount of the catalyst provided in reactor chamber is provided in sample chamber and is contacted with the sample flow. Spectroscopic information is then obtained on the catalyst provided in sample cell, e.g. by an IR spectrometer.

Kits and devices for detecting analytes

The invention provides devices that improve tests for detecting specific cellular, viral, and molecular targets in clinical, industrial, or environmental samples. The invention permits efficient detection of individual microscopic targets at low magnification for highly sensitive testing. The invention does not require washing steps and thus allows sensitive and specific detection while simplifying manual operation and lowering costs and complexity in automated operation. In short, the invention provides devices that can deliver rapid, accurate, and quantitative, easy-to-use, and cost-effective tests.