G01N2021/4797

TIME MEASUREMENT DEVICE, FLUORESCENCE LIFETIME MEASUREMENT DEVICE, AND TIME MEASUREMENT METHOD
20230288335 · 2023-09-14 · ·

A time measurement apparatus 10 includes a TAC circuit 12, a measurement gate 11, a control unit 14 for setting a gate dead time, which is a time during which the measurement gate 11 is set to be in the second state, in the measurement gate 11, and the control unit 14 for deriving and outputting time information related to the detection signal based on a measurement signal output from the TAC circuit 12, and the control unit 14 functioning as a setting unit sets a time, which is an integral multiple of a repetition period of fluorescence detected by the detector 4 and is longer than a dead time of the TAC circuit 12 itself, in the measurement gate 11 as a gate dead time.

SYSTEM AND METHOD OF DYNAMIC MICRO-OPTICAL COHERENCE TOMOGRAPHY FOR MAPPING CELLULAR FUNCTIONS

An apparatus for obtaining image data and functional data from a biological sample, the apparatus including: an interferometer configured to acquire interferometric information at a plurality of time points along an imaging plane for which at least one axis of the plane is at least partially along a depth or axial dimension that is based on radiations provided from a reference interfered with by the biological sample; and a processor configured to receive the interferometric information from the interferometer and configured to: process the interferometric information to generate an image of the biological sample along the imaging plane; determine frequency information based on the plurality of time points of the interferometric information, the frequency information reflecting temporal modulations induced by dynamic functions of the biological sample; generate a spatial map of the frequency information, and the spatial map of the frequency information indicating the dynamic functions of the biological sample.

Combination emitter and camera assembly
11754712 · 2023-09-12 · ·

A system and method for controlling an emitter assembly comprising a single electromagnetic radiation source for visualizing a surgical site. The emitter assembly comprises a light valve assembly that is coupled to a control circuit. The emitter assembly is configured to emit visible light, infrared radiation, or a combination thereof in either structured or unstructured formats. The control circuit is configured to control the light valve assembly to control which emitter of the emitter assembly is emitting electromagnetic radiation. The light valve assembly can include light valves for controlling whether an emitter receives electromagnetic radiation. Further, the control circuit can control the wavelength of the electromagnetic radiation emitted by the source in accordance with which emitter is receiving electromagnetic radiation.

ROBOTIC SYSTEMS WITH SEPARATE PHOTOACOUSTIC RECEIVERS
20230046220 · 2023-02-16 ·

A surgical robotic visualization system comprises a first robotic arm, a second robotic arm, a photoacoustic receiver coupled to the first robotic arm, an emitter assembly coupled to the second robotic arm, and a control circuit. The control circuit is configured to cause the emitter assembly to emit electromagnetic radiation toward an anatomical structure at a plurality of wavelengths capable of penetrating the anatomical structure and reaching an embedded structure located below a surface of the anatomical structure, receive an input of the photoacoustic receiver indicative of an acoustic response signal of the embedded structure, and detect the embedded structure based on the input from the photoacoustic receiver.

Surgical visualization of multiple targets

A surgical visualization system is disclosed. The surgical visualization system is configured to identify one or more structure(s) and/or determine one or more distances with respect to obscuring tissue and/or the identified structure(s). The surgical visualization system can facilitate avoidance of the identified structure(s) by a surgical device. The surgical visualization system can comprise a first emitter configured to emit a plurality of tissue-penetrating light waves and a second emitter configured to emit structured light onto the surface of tissue. The surgical visualization system can also include an image sensor configured to detect reflected visible light, tissue-penetrating light, and/or structured light. The surgical visualization system can convey information to one or more clinicians regarding the position of one or more hidden identified structures and/or provide one or more proximity indicators.

Force sensor through structured light deflection

A surgical visualization system is disclosed. The surgical visualization system includes a control circuit communicatively coupled to a straight line laser source, a structured light emitter, and an image sensor; and a memory communicatively coupled to the control circuit. The memory stores instructions which, when executed, cause the control circuit to control the straight line laser source to project a straight laser line reference; control the structured light source to emit a structured light pattern onto a surface of an element of a surgical device; control the image sensor to detect the projected straight laser line and structured light reflected from the surface of the element of the surgical device; and determine a position of the element of the surgical device relative to the projected straight laser line reference.

PATHLENGTH RESOLVED CW-LIGHT SOURCE BASED DIFFUSE CORRELATION SPECTROSCOPY

A system configured to perform the DCS-type measurements with the use of low-coherence continuous-wave (CW) light source at levels of light intensities that are substantially lower and with pathlengths through the tissue that are substantially longer than those afforded by the use of conventional methods. The method includes utilizing the optical detection system to producing signals representing interference between the portion of CW light arriving through reference arm of interferometer and the sample CW light potion that has traversed the sample arm including different paths through the target tissue while switching between first and second of said different paths only by adjusting a delay in the delay line. The spatial resolution of different pathlengths of sample light through tissue is defined by coherence length of CW light.

SURGICAL VISUALIZATION AND MONITORING
20220323066 · 2022-10-13 ·

A surgical visualization system is disclosed. The surgical visualization system is configured to identify one or more structure(s) and/or determine one or more distances with respect to obscuring tissue and/or the identified structure(s). The surgical visualization system can facilitate avoidance of the identified structure(s) by a surgical device. The surgical visualization system can comprise a first emitter configured to emit a plurality of tissue-penetrating light waves and a second emitter configured to emit structured light onto the surface of tissue. The surgical visualization system can also include an image sensor configured to detect reflected visible light, tissue-penetrating light, and/or structured light. The surgical visualization system can convey information to one or more clinicians regarding the position of one or more hidden identified structures and/or provide one or more proximity indicators. In various instances, a robotic camera of the surgical visualization system can monitor and track one or more tagged structures.

Safety logic for surgical suturing systems

A surgical suturing tracking system is disclosed. The surgical suturing tracking system is configured to detect and guide a suturing needle during a surgical suturing procedure. The surgical suturing track system comprises a control circuit configured to predict a path of a needle suturing stroke after receiving an input from a clinician, detect an embedded tissue structure, and assess proximity of the predicted path and the detected embedded tissue structure.

OPERATIVE COMMUNICATION OF LIGHT
20220273288 · 2022-09-01 ·

A surgical access assembly comprises a trocar and a surgical instrument. The trocar comprises a housing and an access tube extending distally from the housing. The housing comprises a hollow light emitter. The housing and the access tube define a lumen extending through the housing and the access tube. The hollow light emitter is configured to project light in the lumen. The surgical instrument comprises an end effector and a shaft extending proximally from the end effector. The shaft comprises an optical receiver positioned within reach of the light from the hollow light emitter. The shaft further comprises a light guide extending from the optical receiver along at least a portion of the shaft toward the end effector.