An optical sensor of the present disclosure detects light reflected by a transported sheet and/or light transmitted through the sheet as well as light emitted from the sheet. The optical sensor includes: a light source configured to irradiate a sheet with excitation light and detection light; a controller configured to keep the light source turned off during each of light-off periods after the emission of the excitation light; and a light receiver configured to receive light resulting from reflection of the detection light by a sheet and/or light resulting from transmission of the detection light through the sheet in each of the light-on periods and receive phosphorescence emitted from the sheet in each of the light-off periods. The controller is configured to generate data of one pixel by summing up output values based on respective phosphorescence components received by the light receiver in each of the light-off periods.

Systems and methods are provided for a UV-VIS spectrophotometer, such as a UV-VIS detector unit included in a high-performance liquid chromatography system. In one example, a system for the UV-VIS detector unit may include a first light source, a signal detector, a flow path positioned intermediate the first light source and the signal detector, a second light source, and a reference detector. The first light source, the signal detector, and the flow path may be aligned along a first axis, and the second light source and the reference detector may be aligned along a second axis, different than the first axis.

The present invention is drawn to devices and systems for allergen detection in a sample. The allergen detection system includes a sampler, a disposable analysis cartridge and a detection device with an optimized optical system. In some embodiments, the allergen detection utilizes aptamer nucleic acid molecules as detection agents. In some embodiments, the nucleic acids are conjugated to magnetic beads or solid surfaces such as glasses, microwells and microchips.

Systems and methods are provided for a UV-VIS spectrophotometer, such as a UV-VIS detector unit included in a high-performance liquid chromatography system. In one example, a system for the UV-VIS detector unit may include a first light source, a signal detector, a flow path positioned intermediate the first light source and the signal detector, a second light source, and a reference detector. The first light source, the signal detector, and the flow path may be aligned along a first axis, and the second light source and the reference detector may be aligned along a second axis, different than the first axis.

An intensity distribution acquirer acquires a first detected intensity distribution detected by a detector with a sample position at which a sample is not present irradiated with light by a standard light source, and acquires a second detected intensity distribution detected by the detector with the sample position at which a sample is not present irradiated with light by an irradiation light source during a first measuring work. An irradiation intensity calculator calculates a radiation intensity at each wavelength of irradiation light of the irradiation light source based on the first detected intensity distribution, the second detected intensity distribution and radiation characteristics of the standard light source. An irradiation photon count calculator calculates an irradiation photon count at each wavelength of irradiation light of the irradiation light source based on an irradiation intensity at each wavelength.

An optical detection system for a capillary electrophoresis instrument is disclosed. The optical detection system comprises an ultraviolet (UV) source and an absorption measurement optical path. The optical path comprises a first plurality of optical elements comprising a first optical fiber array and other elements. The first plurality of optical elements are arranged to obtain a plurality of respective UV beamlets from a UV beam emitted by the UV source and to direct, at least partially using the first optical fiber array, the respective UV beamlets through respective capillaries of a plurality of capillaries and to an absorption detector positioned to detect respective signals for use in obtaining respective UV absorption measurements corresponding to the respective capillaries.

A spatial gradient-based fluorometer featuring a signal processor or processing module configured to: receive signaling containing information about light reflected off fluorophores in a liquid and sensed by a linear sensor array having a length and rows and columns of optical elements; and determine corresponding signaling containing information about a fluorophore concentration of the liquid a fluorophore concentration of the liquid that depends on a spatial gradient of the light reflected and sensed along the length of the linear sensor array, based upon the signaling received.

A pool maintenance system that includes a spectroscopic device that is configured to analyze a fluid of a pool.

A thin-film deposition system deposits a thin-film on a wafer. A radiation source irradiates the wafer with excitation light. An emissions sensor detects an emission spectrum from the wafer responsive to the excitation light. A machine learning based analysis model analyzes the spectrum and detects contamination of the thin-film based on the spectrum.

Disclosed is apparatus (1) for measuring fluorescence and absorbance of a substance in a sample, said apparatus (1) comprising: a flow cell (2) for containing a sample, a first light source (3), a first conductor (5) for transmitting light from the first light source (3) to the flow cell (2) for irradiating a sample contained therein, a second conductor (7) for transmitting light from the flow cell (2) to a sample detector (9) arranged to detect an electromagnetic radiation that has passed through said cell (2), and a processing unit (16) arranged to receive a first signal (31) from a reference detector (15) and a second signal (32) from the sample detector (9) and to determine an absorbance based on said first and second signals (31,32), said apparatus (1) further comprising a second light source (4), a third conductor (6) for transmitting light from the second light source (4) to the cell (2) and wherein the sample detector (9) is further arranged to also detect fluorescence signals in the light that has passed through the flow cell (2). The invention also relates to a method for measuring the absorbance and the fluorescence of a substance in a sample.