The present invention relates to an automated analytical system and an automated method for separating and detecting an analyte, as well as an automated analytical instrument.

Systems and methods include an optimization-based load planning module for laboratory analyzers of bio-fluid samples. The optimization-based load planning module is executable on a computer server and is configured to optimize assay (lab test) assignments across a large number of laboratory analyzers based on one or more of the following user selected and weighted objectives: reduced turn-around-time, load balancing, efficient reagent usage, lower quality assurance costs, and/or improved system robustness. The optimization-based load planning module outputs a load plan comprising computer executable instructions configured to cause a system controller of a laboratory analyzer system to schedule and direct each requested test to be performed at one or more selected laboratory analyzers of the laboratory analyzer system in accordance with the user selected and weighted objectives. Other aspects are also described.

A first screen for displaying information of at least two analysis modules and a second screen for displaying information of only the specific analysis module among the analysis modules are separately displayed based on at least one piece of information among angle information of a display section, position information of the display section, and information of an operation performed on the analysis modules. Thus, the screen corresponding to a situation of an automatic analysis device can be accurately and reliably provided by a user as compared with the conventional one.

Disclosed herein are formulations, substrates, and arrays. Also disclosed herein are methods for manufacturing and using the formulations, substrates, and arrays. Also disclosed are methods for identifying peptide sequences useful for diagnosis and treatment of disorders, and methods for using the peptide sequences for diagnosis and treatment of disorders, e.g., celiac disorder. In certain embodiments, substrates and arrays comprise a porous layer for synthesis and attachment of polymers or biomolecules.

There is provided a nucleic acid extraction method using a cartridge comprising: (a) a driving part of a nucleic acid extraction device is connected to a control rod module disposed in an inner space of the upper body of a piston and a rotation control module coupled to the lower body of the piston; (b) driving the rotation control module and the control rod module, sequentially sucking sample and reagents from the plurality of chambers separated from each other into an interior space, and discharging the mixture of the interior space into the chamber of the cartridge; and (c) driving the rotation control module and the control rod module to suck the reagent inside the master mix bead chamber of the cartridge into the interior space of the piston upper body and then discharge the mixed reagent to a nucleic acid amplification module.

A rheometer docking station and methods of use are provided. Certain of the systems and methods described herein are capable of docking a rheometer to a rheometer docking station. Certain of the systems and methods described herein are capable of locating a rheometer in one, two or three dimensions.

There is provided a piston of a cartridge for extracting nucleic acids comprising: a cylindrical upper body having a hollow; a lower body having two ports; a control rod module combined to the other end of the upper body to seal the other end and move up and down along the hollow; and a rotation control module that is combined to the shaft of the lower body to transmit a driving force to the lower body.

Provided herein are methods and systems of molecular profiling of diseases, such as cancer. In some embodiments, the molecular profiling can be used to identify treatments for a disease, such as treatments that were not initially identified as a treatment for the disease or not expected to be a treatment for a particular disease.

This automated analysis device is provided with a plurality of analysis units for analyzing a specimen, a buffer portion which holds a plurality of specimen racks on which are placed specimen containers holding the specimen, a sampler portion which conveys the specimen racks held in the buffer portion to the analysis units, and a control portion which, when performing a process to deliver the specimen racks to the plurality of analysis units, outputs synchronization signals to all the plurality of analysis units, wherein the analysis unit performs a delivery process starting from the synchronization signal, and the analysis unit performs a delivery process starting from the synchronization signal.

A process and system for handling biological tissue samples through work stations in which at least one work stations includes a plurality of independent work locations. The handling system includes a main transport apparatus operatively connected to input and output stations and to the work stations for moving bidirectionally the samples among these; a plurality of secondary transport apparatuses operatively connected to the main transport apparatus and each respectively operatively connected to independent work locations of one of the work stations and configured to move bidirectionally the samples among these; and a control arrangement of the transport apparatuses for managing routing and handling of the samples in the work stations according to a work protocol associated with the samples and for managing routing and handling of the samples in the work locations according to a workload of the work locations and the work protocol associated with the samples.