[Object] To provide a mixing device capable of accurately mixing a solution in a multi-well plate.

[Solving Means] A mixing device 1 is configured to be attachable to a multi-well plate 30 and includes a casing 100, a plurality of stirrers 11, a plurality of motors 12 as a drive portion, and a mounting portion 16. The casing 100 includes a main surface portion 101 facing an upper surface 301 of the multi-well plate 30. The stirrers 11 protrude from the main surface portion 101 toward wells 31 of the multi-well plate 30. The motors 12 are disposed to the casing 100 and rotate the stirrers 11 about axes thereof. The mounting portion 16 is provided to the casing 100 and is mounted to the multi-well plate 30 to position the casing 100 on the multi-well plate 30.

An automatic analysis device improves the uniformity of a mixed liquid by noise agitation by a dispensing mechanism. The dispensing mechanism agitates a mixed liquid by suctioning the mixed liquid into a reaction vessel by a nozzle and then re-discharging the suctioned mixed liquid into the reaction vessel. When the mixed liquid is re-discharged into the reaction vessel, the nozzle is moved upward at a speed higher than a speed at which the liquid surface of the mixed liquid rises due to the re-discharging of the mixed liquid from the nozzle during a first period and lowers the speed of moving the nozzle upward than the speed during the first period while maintaining or reducing the speed at which the liquid surface of the mixed liquid rises due to re-discharging of the mixed liquid from the nozzle during a second period following the first period.

There is provided a nucleic acid extraction method using a cartridge comprising: (a) a driving part of a nucleic acid extraction device is connected to a control rod module disposed in an inner space of the upper body of a piston and a rotation control module coupled to the lower body of the piston; (b) driving the rotation control module and the control rod module, sequentially sucking sample and reagents from the plurality of chambers separated from each other into an interior space, and discharging the mixture of the interior space into the chamber of the cartridge; and (c) driving the rotation control module and the control rod module to suck the reagent inside the master mix bead chamber of the cartridge into the interior space of the piston upper body and then discharge the mixed reagent to a nucleic acid amplification module.

A sample introduction system provides mixing of a sample and a diluent within the container via gas injection. In one or more implementations, the sample introduction system causes a probe of an autosampler to be inserted into a container containing a sample and a diluent so that an end of the probe is submerged beneath a surface of the diluent and the sample. Gas is then injected through the probe to mix the sample and the diluent within the container. An aliquot of the mixed sample and diluent is then withdrawn through the probe.

A control section causes one dispensing mechanism of either a reagent dispensing mechanism or a sample dispensing mechanism to first discharge a predetermined amount of a liquid into the reaction container, and then, with respect to the cases where the amount of a liquid to be discharged by the other dispensing mechanism is larger or smaller than the amount of the liquid in the reaction container, causes the other dispensing mechanism to discharge the liquid such that the discharge speed in the case where the amount of the liquid to be discharged is larger is decreased relative to the discharge speed in the case where the amount of the liquid to be discharged is smaller.

A parallel preceding system for processing samples is described. In one embodiment, the parallel processing system includes an instrument interface parallel controller to control a tray motor driving system, a close-loop heater control and detection system, a magnetic particle transfer system, a reagent release system, a reagent pre-mix pumping system and a wash buffer pumping system.

Disclosed is a device for contactlessly mixing fluid present on the upper surface of the slide, where the device comprises a first nozzle array and a second nozzle array, the first nozzle array adapted to impart a bulk fluid flow to the fluid present on the upper surface of the slide, and the second nozzle array adapted to impart at least a first regional fluid flow to at least a portion of the fluid present on the upper surface of the slide

A method of processing a sample in a receptacle comprising a plurality of chambers. Each of the chambers is connected to at least one other chamber by a portal and at least a first one of the chambers is formed of a flexible material. The method includes the steps of causing gas bubbles contained in the first chamber to accumulate in a portion of the first chamber, applying a compressive external force to the first chamber to cause some or all of the liquid contents of the first chamber to flow into an interconnected second chamber through a portal connecting the first and second chambers; and preventing the gas bubbles accumulated in a portion of the first chamber from flowing through the portal into the second chamber.

A reaction cuvette according to an embodiment is used for measurement performed by an automatic analyzing device, and is a reaction cuvette that houses a mixed liquid of a reagent and a sample to be measured. The reaction cuvette includes a cuvette main body and an aspiration port. The aspiration port is disposed on the cuvette main body, and allows a fluid to flow into an inner part of the cuvette main body from a bottom surface side of the cuvette main body.

The present invention is related to the field of microfluidics and compound distribution within microfluidic devices and their associated systems. In one embodiment, present invention aims to solve the problem of molecule and compound absorbency into the materials making up laboratory equipment, microfluidic devices and their related infrastructure, without unduly restricting gas transport within microfluidic devices.