The present disclosure is directed to methods and devices for reducing or otherwise mitigating accumulated reagent material and/or fluids within a dispense nozzle of a dispenser.

The dispensing unit includes a disc, a cartridge, and a dispensing holder. The disc has a disc shape and includes a track region provided with recesses and projections alternately arranged in a radial direction. The cartridge includes a penetration hole, and a well is formed by the penetration hole and the track region in a state in which the cartridge is attached to the disc. The dispensing holder includes a holding part to be inserted into the penetration hole, and a guide hole penetrating the holding part. The guide hole has a truncated cone shape in which a first opening diameter on the holding part side is smaller than a second opening diameter on a side opposite to the holding part, and a center line of the guide hole is located on a line passing through the center of the disc and the center of the well.

A sample injection device (100) includes a tubular suction and discharge unit (23) configured to suction a liquid sample (S), contain the sample therein, and discharge the suctioned sample, and at least a portion of an inner wall (23a) of the suction and discharge unit, the portion having the sample contained therewithin, is subjected to a surface treatment (V) to increase an interfacial tension (F) that acts between the inner wall and the sample.

A pipetting apparatus and method capable of detecting a liquid within an intermediate section of a pipette tube of the pipetting apparatus. The intermediate section is located between an upper section of the pipette tube at which a first electrode is arranged and a lower section at which a second electrode is arranged. The first and second electrodes form a measurement capacitor and are operationally connected to an impedance measurement unit, which is adapted to detect whether liquid, such as a portion of a sample liquid or system liquid, is present within the intermediate section based on the measured impedance or change of impedance, e.g. an increase of the capacitance and/or a decrease of the resistance, of the measurement capacitor caused by a presence of the liquid within the intermediate section.

The present disclosure is directed to methods and devices for reducing or otherwise mitigating accumulated reagent material and/or fluids within a dispense nozzle of a dispenser.

A nucleic acid extraction system, comprising: a nucleic acid extraction plate, and a pipetting device and positive pressure device that are arranged side by side, the pipetting device comprising: an infusion device, an infusion device mounting frame, an infusion device driving unit, and a plurality of infusion units, each of the infusion units comprising: a reagent supply device and a reagent flow controller; the positive pressure device comprises: a plug, an air pipe, a positive pressure provider and a positive pressure driving device. The nucleic acid extraction system is highly efficiency and low-cost when extracting nucleic acid.

The invention relates to a method for transferring a first sample liquid from a first primary vessel into a first target vessel and a second sample liquid from a second primary vessel into a second target vessel with the aid of at least one automated pipetting apparatus comprising a system liquid in an automated analysis machine comprising a control machine.

Systems and methods for analysing a fluid including a fluid sample delivery application. The system includes a sensing element configured to respond to at least one analyte in a sample of fluid. A detector is provided, configured to sense the response to the analyte by the sensing element. The fluid sample delivery apparatus includes a dosage needle configured to deliver the sample of fluid to the sensing element, at least one pump configured to control flow of fluid through the dosage needle, and at least one actuator configured to move the dosage needle relative to the sensing element. At least one controller is provided, configured to control the at least one pump and the at least one actuator.

A sample injection device (100) includes a tubular suction and discharge unit (23) configured to suction a liquid sample (S), contain the sample therein, and discharge the suctioned sample, and at least a portion of an inner wall (23a) of the suction and discharge unit, the portion having the sample contained therewithin, is subjected to a surface treatment (V) to increase an interfacial tension (F) that acts between the inner wall and the sample.

A pipetting apparatus and method capable of detecting a liquid within an intermediate section of a pipette tube of the pipetting apparatus. The intermediate section is located between an upper section of the pipette tube at which a first electrode is arranged and a lower section at which a second electrode is arranged. The first and second electrodes form a measurement capacitor and are operationally connected to an impedance measurement unit, which is adapted to detect whether liquid, such as a portion of a sample liquid or system liquid, is present within the intermediate section based on the measured impedance or change of impedance, e.g. an increase of the capacitance and/or a decrease of the resistance, of the measurement capacitor caused by a presence of the liquid within the intermediate section.