A system and method for ejecting one or more fluids from a digital dispense device. The method includes a) inputting to a memory a volume per unit area for each of the one or more fluids to be ejected from the digital dispense device; b) matching the volume per unit area to a device resolution for the digital dispense device; c) formatting fluid ejectors for the digital dispense device for the device resolution; and d) ejecting fluid from the digital dispense device to provide the volume per area for each of the one or more fluids.

In one example an apparatus can include a controller communicatively coupled to a droplet dispenser to deposit antibody fluid on a matrix of an immunoblotting array, the controller is to align the droplet dispenser with a protein band included in the matrix, instruct the droplet dispenser to deposit a first antibody fluid on to the protein band of the matrix, and instruct the droplet dispenser to deposit a second antibody fluid on to the protein band of the matrix, adjacent to the first antibody fluid.

Provided is a method for producing a cell contained base, the method being capable of providing a cell contained base highly accurately controlled in number of nucleic acid molecules contained in a low-concentration nucleic acid standard sample, the method including a liquid droplet discharging step of discharging a cell suspension in the form of a liquid droplet with a liquid droplet discharging unit onto a base including at least one cell contained region; a cell number counting step of counting a number of cells contained in the liquid droplet with a plurality of sensors from two or more directions while the liquid droplet is flying into the cell contained region; and a liquid droplet landing step of landing the liquid droplet in the at least one cell contained region in a manner that a predetermined number of cells are located in the at least one cell contained region.

Devices and methods for the deposition of reagents onto cells or tissue samples are disclosed. Also disclosed are reagent compositions suitable for dispensing via a droplet-on-demand system.

A liquid discharging device to be used with a liquid dispensing apparatus includes a discharging portion configured to discharge a liquid based on a control signal from the liquid dispensing apparatus on which the liquid discharging device is mounted, and a sheet material having a characteristic configured to be changed by the liquid dispensing apparatus after a discharge of the liquid by the discharging portion.

A unitary, molded fluid reservoir body to which a fluid ejection head substrate is attached. The unitary, molded fluid reservoir body includes one or more discrete fluid chambers therein. Each of the one or more fluid chambers have an open top, side walls, and sloped bottom walls attached to the side walls, wherein each of the one or more fluid chambers terminates in a fluid supply via, and wherein the sloped bottom walls have an angle ranging from about 6 to about 12 degrees relative to a plane orthogonal to the sidewalls. An ejection head support face is disposed opposite the open top for attachment of a single fluid ejection device to the ejection head support face for ejecting fluid provided from the one or more chambers through the one or more fluid supply vias.

A microscope system includes a microscope stage having a top surface configured to have a sample carrier arranged thereon, the sample carrier being configured to receive at least one sample. The microscope system also includes an imaging system configured to image the at least one sample. The microscope system also includes an injector configured to inject a predetermined amount of a liquid into the sample carrier by injecting multiple successive and temporally spaced jets of the liquid into the sample carrier, each jet including a predetermined portion of the amount of liquid.

A digital dispense system and methods for preparing samples for analysis. The digital dispense system includes a fluid droplet ejection system housed in a housing unit. The fluid droplet ejection system contains a fluid droplet ejection head and fluid cartridge containing one or more fluids to be dispensed. A cartridge translation mechanism is provided for moving the fluid droplet ejection head and fluid cartridge back and forth over a sample holder in an x direction. A sample tray translation mechanism moves a sample tray back and forth beneath the fluid droplet ejection head and fluid cartridge in a y direction orthogonal to the x direction.

A system and method for ejecting one or more fluids from a digital dispense device. The method includes a) inputting to a memory a volume per unit area for each of the one or more fluids to be ejected from the digital dispense device; b) matching the volume per unit area to a device resolution for the digital dispense device; c) formatting fluid ejectors for the digital dispense device for the device resolution; and d) ejecting fluid from the digital dispense device to provide the volume per area for each of the one or more fluids.

Devices and methods for the deposition of reagents onto cells or tissue samples are disclosed. Also disclosed are reagent compositions suitable for dispensing via a droplet-on-demand system.