A component extraction apparatus includes a rack placement part, a heater, an extraction medium supply part, a needle assembly, and a temperature sensor. When the container rack is mounted on the rack placement part, a heater is configured to heat the sample containers in direct or indirect contact with sample containers held by the container rack. The needle assembly holds a needle with a tip thereof pointing downward, and the needle being configured to connect a flow channel by inserting the tip thereof into a needle port provided on an upper surface of each of the sample containers. The temperature sensor is included in the needle assembly and is configured to detect a temperature of the upper surface of any one of the sample containers when the tip of the needle is inserted into the needle port of the one of the sample containers.

A point-of-care testing (POCT) fully-automatic chemiluminescence device based on a multi-channel parallel pretreatment technology includes a support. The support is provided thereon with a reaction chamber assembly, which reciprocates linearly relative to the support. A multi-channel parallel pretreatment assembly and a photomultiplier tube (PMT) assembly are arranged on the support and are located above the reaction chamber assembly. The multi-channel parallel pretreatment assembly is configured to transfer, clean, and separate reagents in reagent strips in the reaction chamber assembly. The PMT assembly is configured to detect a luminescence value of the cleaned and separated reagents. The device does not have a liquid passage, resulting in low maintenance costs and high reliability. This realizes automatic sample addition, supports whole blood testing, and avoids carry-over. The device solves the problems in the traditional POCT chemiluminescence device of manual sample addition, cumbersome steps, and human errors which are easily made.

The present invention is an automated separation system comprised of a liquid handling device and one or more pipette tip columns, wherein the liquid handling device is equipped with two or more nozzles arranged to respectively receive a pipette tip column comprising separation media. Further, the system includes means for applying either high positive or negative pressure to the column inside chamber above the column bed, enabling aspiration and dispensing into and out of each pipette tip column. To enable sealing to the pressures used to move liquid through the column bed without inadvertently ejecting the column from the nozzle during the separation process, each nozzle has been provided with at least one annular protrusion arranged to engage with the inside of a substantially evenly tapered pipette tip column, without any corresponding recess. Each nozzle may be provided with slide ejector to enable the removal of a pipette tip column.

Provided is a device for extracting and detecting nucleic acids, comprising one or more sample receiving modules, one or more lysing modules, one or more extraction module of nucleic acids, one or more amplification module of nucleic acids, and a detection module. Also provided is a molecular in vitro diagnostic instrument comprising the device for extracting and detecting nucleic acids and an automatic control system. Further provided is an in vitro diagnosis method by means of performing extraction and amplification of nucleic acids in a sample using the device for extracting and detecting nucleic acids.

The invention relates to an arrangement for preparing a plurality of samples for an analytical method, comprising a carousel with a solid housing and moveable receiving parts for the sample containers; a control for controlling the receiving parts in the carousel; and a sample receiving device for providing the sample for the analytical method. Said arrangement is characterized in that one or more stations for preparing samples are provided on the carousel, the receiving parts for the sample containers of the carousel can be positioned on said stations. Said arrangement also comprises a centrifuge with pairs of opposite lying receiving parts provided for the sample containers, and said receiving parts are arranged such that they can move on the centrifuge for the sample holder such that a transfer of a sample holder between a receiving part in the carousel and a receiving part in the centrifuge can be carried out. The control takes place by the same control which is also provided for controlling the carousel.

In accordance with one embodiment of the present invention, there is disclosed an apparatus for nucleic acid extraction and an operation method thereof. The apparatus for nucleic acid extraction includes: a first rack having a plurality of sample tube receivers arranged in a circle; a second rack having a plurality of elution tube receivers arranged in a circle on an outer side thereof and a washing solution receiver positioned at the center thereof, a part of the washing solution receiver extending outwards to have projections formed in alternation with a plurality of the elution tube receivers; a main body having the first and second racks arranged to position the first rack on the top of the second rack; a rotational driver for separately rotating the first and second racks; a dispenser for separately dispensing a washing solution and an eluting solution into sample tubes; and a pressurizer for maintaining the inside of the sample tubes under raised pressure.

The present invention provides a preprocessing device of a more compact structure, and an analysis system provided with the same. A preprocessing device (1) includes a container holding section (12), a filtration port (30), and a transport arm (24). The container holding section (12) holds a separation container (50) and a collection container (54). The filtration port (30) separates a sample by applying pressure to a sample in the separation container (50). The transport arm (24) transports the separation container (50) and the collection container (54) held by the container holding section (12) from a predetermined transport position. The container holding section (12) holds the separation container (50) and the collection container (54) in an annular or arch-shaped holding region formed on an outer circumference of the filtration port (30), and sequentially moves the separation container (50) and the collection container (54) to the transport position by shifting the separation container (50) and the collection container (54) in the circumferential direction of the holding region.

A pre-analysis treatment device usable for an amino acid, organic acid, and glucide includes an ion-exchange unit configured to load a test sample on a solid-phase cartridge S having a strong ion-exchange resin phase, to allow the strong ion-exchange resin phase to adsorb a predetermined organic compound, then supply a dehydration solvent to dehydrate the strong ion-exchange resin phase, and a derivatization unit configured to feed a predetermined amount of the derivatization reagent to the dehydrated strong ion-exchange resin phase to allow the derivatization reagent to retain for a predetermined time period, thereby trimethylsilylating the organic compound adsorbed on the strong ion-exchange resin phase, and simultaneously desorbing the trimethylsilylated organic compound from the strong ion-exchange resin phase, and then supply a push-out solvent to push the trimethylsilylated organic compound desorbed, out of the solid-phase cartridge S. The device enables at least one organic compound selected from amino acids, organic acids and glucides contained in a test sample to be derivatized and collected easily in a short period of time, and automation of the pre-analysis treatment.

The present invention is directed towards an apparatus and methods for a precise, fast and easy to use manipulation of beads. This method is particularly useful to carry out separation between the beads and the remaining supernants present in the fluid, maximizing the collection and purification efficiencies in tips for liquid handling.

The invention relates to an arrangement (10) for preparing a plurality of samples for an analytical method, comprising a carousel (14) with a solid housing (12) and moveable receiving parts (16) for the sample containers (18); a control for controlling the receiving parts (16) in the carousel (14); and a sample receiving device (24) for providing the sample to be analysed; one or more stations (24, 26, 28, 30, 32) for preparing samples are provided on the carousel (14), the receiving parts (16) for the sample containers (18) of the carousel (14) can be positioned on said stations; a centrifuge (22) with pairs of opposite lying receiving parts (42) provided for the sample containers (18), and said receiving parts (42) are arranged such that they can move on the centrifuge (22) and the movements can be controlled in such a manner that the sample holder (18) can be transferred between a receiving part (16) in the carousel (14) and a receiving part (42) in the centrifuge (22).