Patent classifications
G01N21/69
DETECTION APPARATUS AND DETECTION METHOD
Disclosed is a detection apparatus that transfers magnetic particles through a plurality of chambers in a cartridge which includes the plurality of chambers and a channel connecting between the plurality of chambers, and that causes the magnetic particles to carry a complex of a test substance and a labelling substance, to detect the test substance on the basis of the labelling substance in the complex. The detection apparatus includes: a rotation mechanism configured to rotate the cartridge about a rotation shaft; a magnet configured to collect the magnetic particles in the chambers; a movement mechanism configured to move the magnet in a direction different from a circumferential direction of a circle in which the rotation shaft is centered; a detector configured to detect the test substance; and a controller programmed to control the rotation mechanism and the movement mechanism so as to transfer the magnetic particles from one of the chambers to another one of the chambers.
DETECTION APPARATUS AND DETECTION METHOD
Disclosed is a detection apparatus that transfers magnetic particles through a plurality of chambers in a cartridge which includes the plurality of chambers and a channel connecting between the plurality of chambers, and that causes the magnetic particles to carry a complex of a test substance and a labelling substance, to detect the test substance on the basis of the labelling substance in the complex. The detection apparatus includes: a rotation mechanism configured to rotate the cartridge about a rotation shaft; a magnet configured to collect the magnetic particles in the chambers; a movement mechanism configured to move the magnet in a direction different from a circumferential direction of a circle in which the rotation shaft is centered; a detector configured to detect the test substance; and a controller programmed to control the rotation mechanism and the movement mechanism so as to transfer the magnetic particles from one of the chambers to another one of the chambers.
Electrochemiluminescence method of detecting an analyte in a liquid sample and analysis system
An electrochemiluminescence method of detecting an analyte in a liquid sample and a corresponding analysis system. An analyte in a liquid sample is detected by first providing a receptacle containing a fluid comprising protein coated magnetic microparticles to a stirring unit. Stirring of the fluid is necessary since the density of the microparticles is usually higher than the density of the buffer fluid. Thus the microparticles tend to deposit on the bottom of the receptacle leading to an aggregation of the microparticles because of weak interactions. To obtain representative measurements a homogeneous distribution of the microparticles in the buffer fluid is necessary to ensure a constant concentration of microparticles for each analysis cycle. It is further necessary to provide disaggregation of the microparticles, which is also realized by stirring the fluid. Stirring is conducted with a rotational frequency that is adapted to the amount of fluid to be stirred.
Electrochemiluminescence method of detecting an analyte in a liquid sample and analysis system
An electrochemiluminescence method of detecting an analyte in a liquid sample and a corresponding analysis system. An analyte in a liquid sample is detected by first providing a receptacle containing a fluid comprising protein coated magnetic microparticles to a stirring unit. Stirring of the fluid is necessary since the density of the microparticles is usually higher than the density of the buffer fluid. Thus the microparticles tend to deposit on the bottom of the receptacle leading to an aggregation of the microparticles because of weak interactions. To obtain representative measurements a homogeneous distribution of the microparticles in the buffer fluid is necessary to ensure a constant concentration of microparticles for each analysis cycle. It is further necessary to provide disaggregation of the microparticles, which is also realized by stirring the fluid. Stirring is conducted with a rotational frequency that is adapted to the amount of fluid to be stirred.
ELECTROCHEMICAL CELL DEVICES AND METHODS OF MANUFACTURING
A multi-well assay plate is provided. The multi-well assay plate includes at least a top plate that defines a plurality of wells and a base plate having a substrate with well electrode structures patterned thereon. The well electrode structures are arranged in a plurality of sector electrical structures, each including a working electrode bus bar and a portion of an auxiliary electrode pattern. The substrate further includes at least one working electrode contact patterned on a bottom surface and an auxiliary electrode contact pattern disposed on the bottom surface.
Solution Glow Discharge Plasma Chamber with Lens
An aspect of some embodiments of the present invention relates to a plasma chamber for containing a solution electrode glow discharge (SEGD) apparatus, the plasma chamber comprising a hollow body and a lens. The hollow body is configured to enclose a plasma generated between a solid electrode and a solution electrode, and includes at least one viewing port for letting light generated from the plasma leave the hollow body. The lens is disposed at or near the viewing port, the lens being configured to collect light from the plasma and direct the light onto a light receiving unit.
Solution Glow Discharge Plasma Chamber with Lens
An aspect of some embodiments of the present invention relates to a plasma chamber for containing a solution electrode glow discharge (SEGD) apparatus, the plasma chamber comprising a hollow body and a lens. The hollow body is configured to enclose a plasma generated between a solid electrode and a solution electrode, and includes at least one viewing port for letting light generated from the plasma leave the hollow body. The lens is disposed at or near the viewing port, the lens being configured to collect light from the plasma and direct the light onto a light receiving unit.
Solution Glow Discharge Plasma Chamber with Ventilation
A plasma chamber for containing a solution electrode glow discharge (SEGD) apparatus, the plasma chamber comprising a hollow body and a ventilation unit. The hollow body is configured to enclose a plasma generated between a solid electrode and a solution electrode, the hollow body comprising an inlet opening, an outlet opening, and at least one viewing port for letting light generated from the plasma leave the hollow body. The ventilation unit is configured to move air from outside the hollow body into the inlet, through a portion of the hollow body located between the viewing port and a gap between the solid electrode and the solution electrode, and out of hollow body from the outlet, thereby creating an air curtain for removal from an optical path between the plasma and the viewing port of at least some vapor created by vaporization of liquid in the plasma.
Solution Glow Discharge Plasma Chamber with Ventilation
A plasma chamber for containing a solution electrode glow discharge (SEGD) apparatus, the plasma chamber comprising a hollow body and a ventilation unit. The hollow body is configured to enclose a plasma generated between a solid electrode and a solution electrode, the hollow body comprising an inlet opening, an outlet opening, and at least one viewing port for letting light generated from the plasma leave the hollow body. The ventilation unit is configured to move air from outside the hollow body into the inlet, through a portion of the hollow body located between the viewing port and a gap between the solid electrode and the solution electrode, and out of hollow body from the outlet, thereby creating an air curtain for removal from an optical path between the plasma and the viewing port of at least some vapor created by vaporization of liquid in the plasma.
Apparatus for analyzing the elemental composition of a liquid sample and methods of using the same
A device and method is described for analysing the elemental composition of a liquid sample utilizing a combination of electrochemical pre-concentration followed by spectrochemical analysis of analytes in a single device. The device consists of two electrodes for the purpose of pre-concentration of the analyte ions by electrodeposition, a DC power supply/potentiostat/galvanostat, a high voltage power supply capable of creating an electrical discharge such as arc, spark, glow discharge or plasma, a spectrometer capable of recording a spectrum generated during such discharges as well as a pump(s) for pumping the analyte containing solution. Such a device is autonomous, field-deployable and capable of providing online analysis.