G01N2291/02809

Detection of cardiac troponin or biological markers via shear horizontal surface acoustic wave biosensor using a wet-dry bioanalytical technique

The illustrated embodiments include a method of operating a SAW sensor to detect a sample in a fluid which includes the steps of: providing a SAW sensor with a functionalized detection lane in a handheld, portable assay device and sensor system; maintaining the functionalized detection lane of the SAW sensor dry until the sample is fluidically disposed in the detection lane; fluidically disposing the sample in the functionalized detection lane; removing fluid the functionalized detection lane to concentrate the sample in the functionalized detection lane to increase the probability of a specific antibody-antigen interaction; washing the functionalized detection lane so that substantially only the specific antigen-antibody interaction remains in the functionalized detection lane; removing fluid from the functionalized detection lane again; and measuring concentration of the sample while the functionalized detection lane is fluid-free.

RESONATOR STRUCTURE FOR MASS SENSING
20230023769 · 2023-01-26 ·

A solid mount resonator sensor has a substrate. An anti-reflector stack is disposed proximate the substrate. The anti-reflector stack includes one or more acoustic interference layers. A first electrode is disposed proximate the anti-reflector stack. A second electrode having a first surface facing towards the first electrode and an opposing second surface facing away from the first electrode. A substantially quarter-wave piezoelectric material layer is disposed between the first and second electrodes.

Evaluation method for thermal expansion properties of titania-containing silica glass body, and manufacturing method for titania-containing silica glass body
11555796 · 2023-01-17 · ·

The present invention relates to a method for evaluating the thermal expansion properties of a titania-containing glass body. On the basis of measured values, obtained at a certain temperature, for a physical parameter that changes depending on the titania concentration and a physical parameter that changes depending on the fictive temperature, the thermal expansion coefficient of the titania-containing silica glass body and the slope of the thermal expansion coefficient are calculated using a linear relational expression represented by a plurality of physical properties. The thermal expansion properties of the titania-containing silica glass body are evaluated on the basis of the calculated thermal expansion coefficient and thermal expansion coefficient slope.

Liquid information sensor and method of driving the same

The present invention relates to a liquid information sensor comprises at least more than one electrode set including a first electrode, and a second electrode which is disposed spaced apart from the first electrode and to which an alternating current signal is applied between the first electrode and the second electrode; and a ferroelectric layer including a first side in contact with the first electrode and the second electrode and a second side facing the first side and defining a receiving area for receiving the target liquid, and generating sound waves by physical vibration when the AC signal is applied.

SYSTEM AND METHOD FOR SAMPLE PRESERVATION
20230213416 · 2023-07-06 ·

A method is disclosed that permits calculation of reagent concentrations (in SI units) over time and space within a tissue sample as the sample is immersed in the reagent and the reagent diffuses into the tissue sample. The disclosed method has yielded the surprising result that once a formaldehyde concentration at all points within a tissue sample exceeds about 90 mM during a cold step of a cold+hot fixation protocol, the hot step of the fixation protocol can be commenced to provide reliable detection of molecular targets and preservation of tissue morphology in downstream analyses.

Acoustic sensor having waveguide and inspection device

A sensor includes a first element part having a first member and a first element. The first member is a acoustic tubular waveguide and extends along a first direction. The acoustic tubular waveguide includes a first opening and a second opening. A direction from the second opening toward the first opening is along the first direction. The first element includes a vibratile first membrane, and a first supporter supporting the first membrane. The second opening is between the first opening and the first membrane in the first direction. The sensor may be a Piezoelectric Micro electro mechanical systems Ultrasonic Transducer and may be used for inspecting paper and/or resin including detecting thickness of a fed through banknote and/or the presence of foreign matter thereon such as tape. An optical element may alternatively measure the vibration of a membrane from acoustic through transmission instead of an acoustic receiver.

Flow path sensing for flow therapy apparatus

A respiratory flow therapy apparatus including a sensor module can measure a flow rate of gases or gases concentration provided to a patient. The sensor module can be located after a blower and/or mixer. The sensor module can include at least an ultrasonic transmitter, a receiver, a temperature sensor, a pressure sensor, a humidity sensor and/or a flow rate sensor. The receivers can be immersed in the gases flow path. The receivers can cancel delays in the transmitters and improve accuracy of measurements of characteristics of the gases flow. The receivers can allow for detection of a fault condition in a blower motor of the apparatus.

Concentration measuring instrument

A concentration measuring instrument includes a piezoelectric vibrator transmitting an ultrasonic wave into a solution contained in a cavity and detecting the ultrasonic wave reflected, a temperature sensor measuring a temperature of the solution, a drive circuit generating a drive signal driving the piezoelectric vibrator, a phase comparator performing a phase comparison between the drive signal and a detection signal, a frequency setting circuit making the drive circuit generate drive signals having sequentially different frequencies and monitoring a phase comparison result to detect a resonant frequency, and a Phase Locked Loop (PLL) circuit making a frequency of the drive signal follow the detected resonant frequency. A microcomputer determines a concentration of a solute in the solution on a basis of the frequency of the drive signal while the PLL circuit is being operated and a result of a temperature measurement by the temperature sensor.

Methods and systems for characterizing multiple properties of cement using p-waves of multiple frequencies

Methods and systems for characterizing multiple properties of a cement composition for use at downhole conditions using ultrasonic analysis tools are provided. In some embodiments, the methods comprise: transmitting at least a first p-wave and a second p-wave having different frequencies through a cement composition; determining velocities of the first and second p-waves through the sample; transmitting at least a third p-wave having a third frequency through the cement composition while allowing the cement composition to at least partially hydrate, wherein the third frequency is higher than the second frequency; determining at least a velocity of the third p-wave through the cement composition; based at least in part on the velocities of the p-waves, determining at least the compressibility, Poisson's ratio, Young's modulus, and shear modulus of the cement composition.

Ultrasonic fluid flow measuring system with ultrasonic transducers provided in chambers formed through the pipe wall into the flow passage
11525718 · 2022-12-13 · ·

An ultrasonic measuring device for the measurement of a flow of a fluid, includes a measuring tube, a first chamber and a second chamber. The measuring tube has a central axis, which defines a flow direction for the fluid; The first chamber has a first ultrasonic transducer arranged therein. The second chamber has a second ultrasonic transducer arranged therein. The measuring tube includes an inlet and an outlet for the fluid. The first ultrasonic transducer and the second ultrasonic transducer bound a rectilinear measuring section for the fluid, the first chamber and the second chamber being configured and arranged such that the fluid is capable of flowing around each of them. The first ultrasonic transducer and the second ultrasonic transducer are arranged such that the measuring section extends in the flow direction.