G01N2333/28

MEANS TO DETECT WHETHER ACUTE HEPATOPANCREATIC NECROSIS DISEASE-CAUSING VIBRIO PARAHAEMOLYTICUS IS VIRULENT OR NON-VIRULENT
20220326237 · 2022-10-13 ·

A method of monitoring acute hepatopancreatic necrosis disease in shrimp is disclosed. More specifically, detection of the presence of alkaline phosphatase Phox enzyme, or, of the PiRA.sup.VP and/or the PirB.sup.VP toxins of acute hepatopancreatic necrosis disease-causing Vibrio parahaemolyticus correlates with non-virulence or virulence, respectively, of the bacterium is disclosed. Hence, an assay capable of detecting the Phox enzyme and/or the toxins could be very useful to monitor the disease in shrimp.

RAPID LATERAL FLOW ASSAY FOR VIBRIO DETECTION

The present disclosure relates to methods, devices, assays and systems for rapid detection of food-borne pathogens, including Vibrios.

ELECTROCHEMICAL TYROSINASE ENZYME IMMUNOASSAY BIOSENSOR AND SYSTEMS AND METHODS RELATED THERETO
20170299581 · 2017-10-19 ·

Devices, assays and methods for detecting analytes in a sample are provided. Biosensor devices include a biosensor interface that includes enzyme-conjugated molecules, antibodies and an enzyme driven redox cycle coupled to an electrically conductive electrode for signal amplification. The biosensor devices are easily adaptable to a variety of assay formats, a variety of target analytes and provide real-time measurements combined with high sensitivity and high specificity for the analyte.

Anti-HERV-K envelope protein antibodies and methods for detecting HERV-K envelope protein in patients with sporadic amyotrophic lateral sclerosis

The present invention relates to a novel antibody against HERV-K envelope that targets a conserved region not affected by glycosylation or by native conformation, and its use in diagnostics and/or is therapy.

Synthetic hybrid receptor and genetic circuit in bacteria to detect enteric pathogenic microorganisms

Provided herein are microorganisms engineered with hybrid receptors and genetic circuits. Also provided are hybrid receptors having a CqsS polypeptide and a heterologous histidine kinase domain of a two-component system. Methods for using engineered microorganisms to sense and destroy pathogens (e.g., Vibrio cholerae) are also provided.

ANTI-HERV-K ENVELOPE ANTIBODY AND USES THEREOF

The present invention relates to a novel antibody against HERV-K envelope that targets a conserved region not affected by glycosylation or by native conformation, and its use in diagnostics and/or is therapy.

Methods for alleviating symptoms of sporadic amyotrophic lateral sclerosis by neutralizing a HERV-K envelope protein using an anti-HERV-K envelope protein antibody

The present invention relates to a novel antibody against HERV-K envelope that targets a conserved region not affected by glycosylation or by native conformation, and its use in diagnostics and/or in therapy.

SYNTHETIC HYBRID RECEPTOR AND GENETIC CIRCUIT IN BACTERIA TO DETECT ENTERIC PATHOGENIC MICROORGANISMS

Provided herein are microorganisms engineered with hybrid receptors and genetic circuits. Also provided are hybrid receptors having a CqsS polypeptide and a heterologous histidine kinase domain of a two-component system. Methods for using engineered microorganisms to sense and destroy pathogens (e.g., Vibrio cholerae) are also provided.

Vibrio assay methods and kits

Methods and kits for detection of bacteria, especially Vibrio parahaemolyticus and Vibrio vulnificus, are provided using a unique combination of selective ingredients and two-phase culture (solid-phase culture gel and liquid-phase culture/enrichment broth) allows for high sensitivity and specificity of the kits for growth of Vibrio parahaemolyticus and Vibrio vulnificus in the detection methods and kits. The invention, through the detection mechanism accomplished by the novel formulation of selective ingredients and the two-phase culture, allows for real-time detection of a single cell of Vibrio parahaemolyticus and Vibrio vulnificus within 242 hours of introducing a target sample to the Vibrio parahaemolyticus and Vibrio vulnificus detection kits.

ANTI-HERV-K ENVELOPE ANTIBODY AND USES THEREOF

The present invention relates to a novel antibody against HERV-K envelope that targets a conserved region not affected by glycosylation or by native conformation, and its use in diagnostics and/or in therapy.