A system for detecting analytes in a test sample, and a method for processing the same, is provided. The system includes a cartridge reader unit that has a control unit and a pneumatic system, and a cartridge assembly that prepares the samples with mixing material(s) through communication channels. The assembly has a memory chip with parameters for preparing the sample and at least one sensor (GMR sensor) for detecting analytes in the sample. The assembly is pneumatically and electronically mated with the reader unit via a pneumatic interface and an electronic interface such that the parameters may be implemented via the control unit. The pneumatic system is contained within the unit and has pump(s) and valve(s) for selectively applying fluid pressure to the pneumatic interface of the assembly, and thus through the communication channels, to move the sample and mixing material(s) through and to sensor. The control unit activates the pneumatic system to prepare the sample and provide it to the sensor for detecting analytes, and also processes measurements from the sensor to generate test results.

A system for detecting analytes in a test sample, and a method for processing the same, is provided. The system includes a cartridge reader unit that has a control unit and a pneumatic system, and a cartridge assembly that prepares the samples with mixing material(s) through communication channels. The assembly has a memory chip with parameters for preparing the sample and at least one sensor (GMR sensor) for detecting analytes in the sample. The assembly is pneumatically and electronically mated with the reader unit via a pneumatic interface and an electronic interface such that the parameters may be implemented via the control unit. The pneumatic system is contained within the unit and has pump(s) and valve(s) for selectively applying fluid pressure to the pneumatic interface of the assembly, and thus through the communication channels, to move the sample and mixing material(s) through and to sensor. The control unit activates the pneumatic system to prepare the sample and provide it to the sensor for detecting analytes, and also processes measurements from the sensor to generate test results.

Devices and methods for molecule detection using such devices are disclosed herein. A molecule detection device comprises at least one fluidic channel configured to receive molecules to be detected, a sensor comprising a spin torque oscillator (STO) and encapsulated by a material separating the sensor from the at least one fluidic channel, and detection circuitry coupled to the sensor. At least some of the molecules to be detected are labeled by magnetic nanoparticles (HNPs). A surface of the material provides binding sites for the molecules to be detected. The detection circuitry is configured to detect a frequency or frequency noise of a radio-frequency (RF) signal generated by the STO in response to presence or absence of at least one MNP coupled to one or more binding sites associated with the sensor.

In a system for affinity selection by mass spectrometry, wherein a plurality of drug candidates in solution are separated based on affinity, a method is provided comprising introducing a solid-phase device having binding affinity for a selected protein into the solution, binding at least one of the plurality of drug candidates to the solid-phase device as a selected drug candidate, washing the solid-phase device and selected drug candidate to separate unbound material, sampling the selected drug candidate in capture fluid flowing through a sampling region of an open port sampling interface and directing the sampled selected drug candidate and capture fluid to an ionization source.

Apparatus and method are provided wherein by measuring both the electrical permittivity and the electrical conductivity of the measured multiphase fluid, the resultant amplitude and phase angle of the induced complex voltage can be analysed. The phase angle data can be analysed to provide information on the electrically conductive phase, and that information can be employed to analyse the amplitude data, in particular to use the information on the electrically conductive phase to determine the contribution to the amplitude data by the electrically non-conductive phase. This analytical technique enables the electrical permittivity of the electrically non-conductive phase to be accurately determined. By determining the degree of contribution to the complex voltage measurement by both the permittivity and the conductivity, enhanced measurement accuracy of a multiphase fluid can be achieved.

Apparatus and method are provided wherein by measuring both the electrical permittivity and the electrical conductivity of the measured multiphase fluid, the resultant amplitude and phase angle of the induced complex voltage can be analysed. The phase angle data can be analysed to provide information on the electrically conductive phase, and that information can be employed to analyse the amplitude data, in particular to use the information on the electrically conductive phase to determine the contribution to the amplitude data by the electrically non-conductive phase. This analytical technique enables the electrical permittivity of the electrically non-conductive phase to be accurately determined. By determining the degree of contribution to the complex voltage measurement by both the permittivity and the conductivity, enhanced measurement accuracy of a multiphase fluid can be achieved.

An electromagnetic sensor for use in an apparatus for measuring electromagnetic properties of a fluid and/or a solid, the sensor comprising a substrate in the form of a plate, a plurality of first sensor elements on the substrate, the first sensor elements forming a first array of the first sensor elements on the substrate, a plurality of second sensor elements on the substrate, the second sensor elements forming a second array on the substrate, wherein the first and second arrays are regular arrays and are mutually aligned geometrically, a plurality of electrical connectors on the substrate, and a plurality of electrical terminals on the substrate, the electrical connectors electrically connecting the first and second sensor elements to electrical terminals, wherein the first sensor elements each comprise a first type of sensor selected from an inductive sensor, a capacitive sensor and a magnetic sensor and the second sensor elements each comprise a second type of sensor selected from an inductive sensor, a capacitive sensor and a magnetic sensor, wherein the first type of sensor and the second type of sensor are different.

An electromagnetic sensor for use in an apparatus for measuring electromagnetic properties of a fluid and/or a solid, the sensor comprising a substrate in the form of a plate, a plurality of first sensor elements on the substrate, the first sensor elements forming a first array of the first sensor elements on the substrate, a plurality of second sensor elements on the substrate, the second sensor elements forming a second array on the substrate, wherein the first and second arrays are regular arrays and are mutually aligned geometrically, a plurality of electrical connectors on the substrate, and a plurality of electrical terminals on the substrate, the electrical connectors electrically connecting the first and second sensor elements to electrical terminals, wherein the first sensor elements each comprise a first type of sensor selected from an inductive sensor, a capacitive sensor and a magnetic sensor and the second sensor elements each comprise a second type of sensor selected from an inductive sensor, a capacitive sensor and a magnetic sensor, wherein the first type of sensor and the second type of sensor are different.

The present disclosure relates to a method and apparatus for cleaning a 3D printed article, in particular a 3D printed heat exchanger. After 3D printing, an article may have internal passages formed from bonded powder and said passages may contain unbonded powder that needs to be removed before further use of/processing of the article. To remove this unbonded powder, the article is filled with a cleaning fluid and vibrated. The cleaning fluid is then pumped out of the article and past a sensor that generates a magnetic field. The sensor detects the presence of powder particles in the fluid by detecting a perturbation of the magnetic field caused by said particles. The fluid is then filtered and returned to a reservoir for use. The sensor may indicate the article is sufficiently clean when a detected concentration of particles in the fluid drops below a threshold.

A method and apparatus for measuring multiple parameters of drilling fluid using electric field perturbation, permittivity curves, time domain analysis and frequency domain analysis to identify constituents of drilling fluid and ratios of the drilling fluid constituents on a real time basis and to measure volumes and densities of the constituents on a real time basis.